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2022
The discovery and development of the first generations of antidepressants in the last century, the tricyclic antidepressants and serotonin reuptake blockers, were a breakthrough in the pharmacological treatment of major depression. Along with the antidepressant activity came the sexual side effects, which contributed considerably to the high level of ...
Olivier, Jocelien D. A. +4 more
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The discovery and development of the first generations of antidepressants in the last century, the tricyclic antidepressants and serotonin reuptake blockers, were a breakthrough in the pharmacological treatment of major depression. Along with the antidepressant activity came the sexual side effects, which contributed considerably to the high level of ...
Olivier, Jocelien D. A. +4 more
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Pharmacological Features of Masculine Sexual Behavior in an Animal Model of Depression
Pharmacology Biochemistry and Behavior, 1998Neonatal treatment with clomipramine induces behavioral alterations during adulthood that resemble symptoms observed in human depression. Therefore, it has been proposed as an animal model of depression. Impairment of male sexual performance is one of the main effects of this treatment.
H, Bonilla-Jaime +2 more
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Journal of Sexual Medicine, 2011 ABSTRACTIntroductionFemale sexual dysfunction (FSD) affects 33–48% of women. Female rats with low sexual activity might model FSD.AimIn this study, we have investigated whether in a population of normal female rats, subpopulations of rats exist with different levels of sexual behavior.MethodsSexually experienced, intact, estradiol-primed female rats ...
Eelke M S Snoeren +2 more
exaly +4 more sources
Pharmacology Biochemistry and Behavior, 2014
Female sexual dysfunctions are a heterogeneous group of symptoms with unknown but probably varying etiology. Social factors may contribute both to the prevalence and to the origin of these dysfunctions. The present review focuses on female hypoactive sexual desire disorder, sexual arousal disorder and orgasmic disorder.
Anders Ågmo
exaly +3 more sources
Female sexual dysfunctions are a heterogeneous group of symptoms with unknown but probably varying etiology. Social factors may contribute both to the prevalence and to the origin of these dysfunctions. The present review focuses on female hypoactive sexual desire disorder, sexual arousal disorder and orgasmic disorder.
Anders Ågmo
exaly +3 more sources
Scandinavian Journal of Psychology, 1980
Some aspects of the experimental study of hormonally controlled sexually dimorphic behavior patterns are discussed, using results derived from research on rat and guinea pig sexual behavior as the model. The traditional concept that sex differences in behavior are due to differences in hormone sensitivity may be only partially correct and it is ...
P. SÖDERSTEN, S. HANSEN
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Some aspects of the experimental study of hormonally controlled sexually dimorphic behavior patterns are discussed, using results derived from research on rat and guinea pig sexual behavior as the model. The traditional concept that sex differences in behavior are due to differences in hormone sensitivity may be only partially correct and it is ...
P. SÖDERSTEN, S. HANSEN
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An Alternative Animal Model for the Study of Female Sexual Behavior
Current Directions in Psychological Science, 1995The white rat has long reigned as the preferred model to study various aspects of physiological psychology, including reproductive behavior. Rats were initially selected for labo ratory experimentation in part be cause of their ability to reproduce copiously and rapidly in captivity. Although this is a good criterion to use to select a model, it is not
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Sexual Behavior in Rats: An Animal Model for the Study of the Neuroendocrine System
2016Although the influence of gonads on sexual behavior has been empirically known for a number of centuries, it was not until the pioneering studies of Brown-Sequard and Steinach at the beginning of the twentieth century that this relationship was scientifically analyzed.
M. Jennifer Rodriguez +5 more
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Psychopharmacology, 1985
Oxotremorine (0.1-0.8 mg/kg IP), but not arecoline (12-48 mg/kg IP), or pilocarpine (5-20 mg/kg IP), reduced both the number of intromissions to ejaculation and the ejaculation latency in methscopolamine-pretreated male rats. The effects of oxotremorine, (0.4 mg/kg IP) were completely antagonized by the administration of scopolamine (0.4 mg/kg IP ...
S, Ahlenius, K, Larsson
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Oxotremorine (0.1-0.8 mg/kg IP), but not arecoline (12-48 mg/kg IP), or pilocarpine (5-20 mg/kg IP), reduced both the number of intromissions to ejaculation and the ejaculation latency in methscopolamine-pretreated male rats. The effects of oxotremorine, (0.4 mg/kg IP) were completely antagonized by the administration of scopolamine (0.4 mg/kg IP ...
S, Ahlenius, K, Larsson
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Eksperimental'naia i klinicheskaia farmakologiia, 1993
Behavioral methods were used to examine the features of effects of fenazepam. gidazepam, and medazepam in young and mature non-inbred albino male rats. There were age- [correction of sex-]specific differences in responses to a drug. The higher effects the drug possesses, the greater differences there are in its effects on animals of different ages.
T A, Voronina +2 more
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Behavioral methods were used to examine the features of effects of fenazepam. gidazepam, and medazepam in young and mature non-inbred albino male rats. There were age- [correction of sex-]specific differences in responses to a drug. The higher effects the drug possesses, the greater differences there are in its effects on animals of different ages.
T A, Voronina +2 more
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EFFECT OF DRONE BROOD HOMOGENATE ON THE SEXUAL BEHAVIOR OF LABORATORY ANIMALS
Scientific Notes Kazan Bauman State Academy of Veterinary Medicine, 2022E.V. Zdoroveva +4 more
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