From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The Sexual Behavior of Male Sexual Partner of Tranvestite in the Prevention Efforts of HIV/AIDS Transmission [PDF]
, 2016 Transvestite is one of the high risk groups in HIV/AIDS. Integrated Biological and Behavioral Surveillance (IBBS) states that in 2011, the HIV prevalence among waria in Indonesia has reached 22%, increasing from 2009 (18.96%).
Azinar, M. (Muhammad) +1 more
core
Perceived Parental Monitoring on Adolescence Premarital Sexual Behavior in Pontianak City, Indonesia [PDF]
, 2015 Inadaquate parental monitoring is widely recognized as a risk factor for the development of child and adolescent conduct problems, including early premarital sexual behavior.
Adiyanti, M. (MG) +3 more
core +2 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
The Addictive Potential of Sexual Behavior
Impulse: The Premier Undergraduate Neuroscience Journal, 2018 This paper examines the addictive potential of sexual behavior through behavioral and neurophysiological mechanisms analogous to other formalized addictions.
Heather Bool
doaj
Sexual Addiction: Definition, Etiology and Treatment
Psikiyatride Güncel Yaklaşımlar, 2021 In present day, it is known that addiction does not only derive from a psychoactive substance but also from the pleasure and relief after some behaviors.
Gülşah Ezgican Kızılok
doaj +1 more source
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
FEBS Letters, EarlyView.The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran +6 more
wiley +1 more source
RELATIONSHIPS BETWEEN SEXUAL BEHAVIOR AND PERSONALITY IN THE CONTEXT OF SEXUAL DIMORPHISM [PDF]
Psihologija, 2009 The aim of this study was to examine the structure and intensity of relation-ships between dimensions of sexual behavior and personal characteristics in the context of sexual dimorphism. The sample included 233 participants (both genders, mean age 29,34).
Bojana Dinic, Goran Knezevic
doaj
Defining “High-risk Sexual Behavior” in the Context of Substance Use
Journal of Psychosexual Health, 2019 Introduction: Sexual behavior is a behavior exhibited by individuals to gratify one of their basic needs, that is the sexual need. Often the way in which sexual behavior is practiced may lead to negative consequences.
Nishtha Chawla, Siddharth Sarkar
doaj +1 more source
Analysis of Adolescent Sexual Behavior in Bogor Taruna Terpadu Borcess Middle School
Jurnal Ilmu Kesehatan Masyarakat, 2020 Adolescents At This Time Experienced A Very Rapid Social Change From Traditional Society Towards Modern Society, Which In Turn Changed The Values, Norms, Including The Lifestyle Of Adolescents.
Resty Jayanti, Ade Saputra Nasution
doaj +1 more source