Results 51 to 60 of about 6,389,740 (364)

Child Maltreatment and Risky Sexual Behavior

open access: yesChild Maltreatment, 2017
Risky sexual behavior is a serious public health problem. Child sexual abuse is an established risk factor, but other forms of maltreatment appear to elevate risky behavior.
Richard Thompson   +7 more
semanticscholar   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

The Social Behavior and the Evolution of Sexually Transmitted Diseases [PDF]

open access: yes, 2002
We introduce a model for the evolution of sexually transmitted diseases, in which the social behavior is incorporated as a determinant factor for the further propagation of the infection. The system may be regarded as a society of agents where in principle anyone can sexually interact with any other one in the population. Different social behaviors are
arxiv   +1 more source

Sexual Behavior in Penguins [PDF]

open access: yesThe Murrelet, 1951
316 p. illus., map. 24 cm. Bibliography: p. [303]-310.
Martha R. Flahaut, L. E. Richdale
openaire   +2 more sources

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

ANALYSIS OF EXPOSURE OF REPRODUCTIVE HEALTH INFORMATION TOWARDS ADOLESCENT SEXUAL BEHAVIOR

open access: yesJournal of Midwifery, 2021
range of 10 to 19 years. Adolescents are the population in the age range of 10-18 years. Rapid physical changes and hormonal changes are triggers for sexual motivation.
Bernadeta Verawati, Kenik SW
doaj   +1 more source

Compulsive Sexual Behavior: A Review of the Literature

open access: yesJournal of Behavioral Addictions, 2015
Background and Aims Compulsive sexual behavior (CSB) is a common disorder featuring repetitive, intrusive and distressing sexual thoughts, urges and behaviors that negatively affect many aspects of an individual’s life.
K. Derbyshire, J. Grant
semanticscholar   +1 more source

Asexual and sexual replication in sporulating organisms [PDF]

open access: yes, 2006
This paper develops models describing asexual and sexual replication in sporulating organisms. Replication via sporulation is the replication strategy for all multicellular life, and may even be observed in unicellular life (such as with budding yeast).
arxiv   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

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