Results 71 to 80 of about 6,389,740 (364)

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

PERAN KOMUNIKASI DAN POLA ASUH ORANGTUA TERHADAP PERILAKU SEKSUAL SISWA SEKOLAH MENENGAH PERTAMA DI KECAMATAN SUKORAMBI KABUPATEN JEMBER

open access: yesJurnal Ilmu Kesehatan Masyarakat, 2019
Problem high-risk sexual behavior that teens when dating is the responbility of everyone, especially parents.. The parental presence of effective communication and appropriate parenting pattern is expected to cope with the increasing high-risk sexual ...
Holfi Mariyatul Kiptiyah, Ni'mal Baroya
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

RELATIONSHIP OF KNOWLEDGE ABOUT SEXUALLY TRANSMITTED INFECTIONS WITH THE SEXUAL BEHAVIOR OF ADOLESCENT WOMEN IN SMKN 5 JEMBER

open access: yesIndonesian Midwifery and Health Sciences Journal, 2023
Introduction: Adolescence is a period in which hormonal developments affect physical, psychological and cognitive development. At this time adolescents show an interest in sexuality so that adolescents are at risk of contracting Sexually Transmitted ...
Maulidia Fahmadina Rozana   +2 more
doaj  

Sexual Behavior and HIV / AIDS Prevention in Male Sexual Men (MSM) in Denpasar City

open access: yesWMJ (Warmadewa Medical Journal), 2021
HIV / AIDS cases among MSM (male sex men) in Indonesia from year to year have increased significantly. Meanwhile, Bali is a province with many HIV / AIDS cases, where Denpasar is the city with the highest number of MSM.
Luh Gede Pradnyawati, Hegard Sukmawati
doaj   +1 more source

Longitudinal Association Between Teen Sexting and Sexual Behavior

open access: yesPediatrics, 2014
BACKGROUND: This study examines the temporal sequencing of sexting and sexual intercourse and the role of active sexting (sending a nude picture) in mediating the relationship between passive sexting (asking or being asked for a nude picture) and sexual ...
J. Temple, H. Choi
semanticscholar   +1 more source

Finding a Mate With No Social Skills [PDF]

open access: yes, 2015
Sexual reproductive behavior has a necessary social coordination component as willing and capable partners must both be in the right place at the right time. While there are many known social behavioral adaptations to support solutions to this problem, we explore the possibility and likelihood of solutions that rely only on non-social mechanisms.
arxiv   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Co-relationship between sexual dysfunction and high-risk sexual behavior in patients receiving buprenorphine and naltrexone maintenance therapy for opioid dependence

open access: yesIndustrial Psychiatry Journal, 2015
Introduction: People suffering from substance dependence suffer from various sexual dysfunctions and are at risk for indulging in various high-risk sexual behaviors and thus are vulnerable to acquire various infections such as HIV/AIDS and other sexually
Santosh Ramdurg   +2 more
doaj   +1 more source

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