Results 271 to 280 of about 2,384,947 (332)
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Wolbachia infection can bias estimates of intralocus sexual conflict
E Duffy (6020198) +7 more
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The Genomics of Sexual Conflict
The American Naturalist, 2018Sexual dimorphism is a substantial contributor to the diversity observed in nature, extending from elaborate traits to the expression level of individual genes. Sexual conflict and sexually antagonistic coevolution are thought to be central forces driving the dimorphism of the sexes and its diversity.
Rowe, Locke +2 more
openaire +4 more sources
Annals of the New York Academy of Sciences, 2009
Intralocus sexual conflict arises when there are sex‐specific optima for a trait that is expressed in both sexes and when the constraint of a shared gene pool prevents males and females from reaching their optima independently. This situation may result in a negative intersexual correlation for fitness.
Bonduriansky, Russell +1 more
openaire +6 more sources
Intralocus sexual conflict arises when there are sex‐specific optima for a trait that is expressed in both sexes and when the constraint of a shared gene pool prevents males and females from reaching their optima independently. This situation may result in a negative intersexual correlation for fitness.
Bonduriansky, Russell +1 more
openaire +6 more sources

