Results 81 to 90 of about 724,606 (302)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

“No Does Not Always Mean No”: The Discursive Representation of Female Sexual Rejection as “Last Minute Resistance” in Pick-Up Artist Communities

open access: yesInternational Journal of Communication, 2023
This study examines the representation of female sexual rejection within pick-up artist (PUA) communities, which are groups of heterosexual men who aspire to become experts in the “art of seducing women.” Driven by critical discourse analysis, the study
Giuseppina Scotto di Carlo
doaj   +2 more sources

L’inceste et le droit pénal français contemporain : lorsque l’application du droit dans les tribunaux révèle une indicible frontière

open access: yesGlad!, 2018
In the modern French penal code, incest is only considered as an aggravation of criminal offense (rape, sexual offense, indecent assault on minors) when the offender is an ascendant or a person with authority over the victim.
Marie Romero
doaj   +1 more source

Alaska Victimization Survey: From Research to Policy and Practice [PDF]

open access: yes, 2010
This project was supported by the Alaska Council on Domestic Violence and Sexual Assault. Points of view in this document are those of the authors and do not necessarily represent the official position or policies of the Council, the Alaska Department of
Myrstol, Brad A.   +4 more
core  

The question of sexual consent: between individual liberty and human dignity [PDF]

open access: yes, 2015
International audienceIn sexual matters, the concept of consent has recently come to the forefront. The concept allows a distinction to be made, notably from a legal standpoint, between what is considered to be raped and what is not.
Simard, David
core   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Beliefs, Attitudes and Behaviors Related to Sexual Consent in Complex Sexual Scenarios

open access: yesSexes
Sexual consent, although more extensively studied in recent decades, remains a complex and nuanced concept that is often difficult to define and investigate.
Anais Sánchez Arévalo   +4 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Moving Beyond Sexual Consent: Exploring Mutuality as a Standard for Sexual Ethics. An Interview with Sharon Lamb

open access: yesEx Aequo: Revista da Associação Portuguesa de Estudos sobre as Mulheres
In this interview, Sharon Lamb and Maria João Faustino discuss the popularization of sexual consent in a neoliberal framework, the problems concerning consent and the persistence of victim-blaming.
Maria João Faustino
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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