Results 191 to 200 of about 572,921 (245)

Comparative Analysis of Phenotypic and Genotypic Differences Between Individuals Affected by Regressive and Non‐Regressive Autism: A Cross‐Sectional Study

Autism Research, EarlyView.
ABSTRACT Development among autistic youth varies widely. A subgroup of children experiences regression, defined as the loss of previously acquired developmental skills. Various genetic and environmental factors have been suggested as potential contributors.
Seyed Hassan Tonekaboni, Alana Iaboni, Brett Trost, Miriam Reuter, Zsuzsa Lindenmaier, Azadeh Kushki, Elizabeth Kelley, Jessica Jones, Muhammed Ayub, Stelios Georgiades, Robert Nicolson, Elim Chan, Andrada Cretu, Jessica Brian, Evdokia Anagnostou   +14 more
wiley   +1 more source

The Language ENvironment Analysis (LENA) System in Toddlers With Early Indicators of Autism: Test–Retest Reliability and Convergent Validity With Clinical Language Assessments

Autism Research, EarlyView.
ABSTRACT Clinical language assessments often influence the types of services that autistic children are eligible to receive. However, these assessments often take place outside of the child's natural language environment. In this study, we assess the potential of using naturalistic language processing technology, the Language ENvironment Analysis (LENA)
Nicole Nadwodny, Paul J. Yoder, Brooke R. Ingersoll, Allison L. Wainer, Wendy L. Stone, Abbey Eisenhower, Alice S. Carter, The RISE Research Network, Wendy L. Stone, Brooke R. Ingersoll, Allison L. Wainer, Alice S. Carter, R. Christopher Shedrick, Sarabeth Broder‐Fingert, Sarah R. Edmunds   +14 more
wiley   +1 more source

Analysis of 4616 clinical trial initial submissions received by the Medicines and Healthcare products Regulatory Agency between February 2019 and October 2023

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse clinical trial initial submissions received by the MHRA between February 2019 and October 2023. Methods Data on submissions were extracted from the clinical trials unit data bank. The primary end‐point was the type of clinical trial initial submissions.
Andrea Manfrin, Kingyin Lee, James Pound, Munir Pirmohamed, June Raine   +4 more
wiley   +1 more source

EudraVigilance insights: Suspected adverse drug reactions in infants through breastfeeding

British Journal of Clinical Pharmacology, EarlyView.
Aims We aimed to describe suspected adverse drug reactions (ADRs) in infants resulting from medications transmitted through mothers' milk, as reported to the European ADR database, EudraVigilance. The research sought to understand the frequency, seriousness and nature of these ADRs to assess potential risks associated with maternal medication use ...
Ida M. Heerfordt, Ditte Resendal Gotfredsen, Henrik Horwitz, Anette Kirstine Stark, Jon Trærup Andersen, Christina Gade, Ulrik Lausten‐Thomsen, Rasmus Huan Olsen   +7 more
wiley   +1 more source

Towards greener prescribing? Swedish general practitioners' support for policies to reduce pharmaceutical pollution

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing pharmaceuticals is essential to improve health, but it also has substantial environmental impact. This study investigated the extent to which Swedish general practitioners (GPs) are willing to integrate environmental aspects into treatment decisions and their opinions on policies to reduce pharmaceutical pollution.
Johanna Villén, Johanna Laux, Björn Wettermark, Sofia Kälvemark Sporrong, Marmar Nekoro, Helle Håkonsen   +5 more
wiley   +1 more source

Patient, carer and healthcare professional perspectives on deprescribing in surgical wards: A mixed methods study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The perspectives of patients and healthcare professionals regarding deprescribing in surgical wards within hospital settings are unknown. The aim of this study was to explore current practices, attitudes and the enablers and barriers to deprescribing in hospital for older surgical inpatients from the perspectives of doctors, pharmacists ...
Bonnie M. Liu, Janani Thillainadesan, Aili Langford, Kenji Fujita, Danijela Gnjidic, Sarah N. Hilmer   +5 more
wiley   +1 more source

The impact of a preprescribing formative assessment on learning in final‐year medical students using hospital inpatient electronic prescribing systems

British Journal of Clinical Pharmacology, EarlyView.
Aims Graduating medical students consistently report being unprepared for the complexity of prescribing in clinical practice. Current clinical prescribing teaching and authentic assessment are limited due to patient safety concerns. We aimed to examine the educational utility of supervised preprescribing as a learning process and potential authentic ...
Kellie A. Charles, Lorna Pairman, Emily Moon, Daniel Wong, John Quayle, Tim J. Wilkinson, Matthew Doogue, Paul Chin   +7 more
wiley   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Young children's right to be heard on the quality of their education: Addressing potential misunderstandings in the context of early childhood education

British Educational Research Journal, EarlyView.
Abstract In early childhood education many researchers and professionals across the world have embraced the United Nations Convention on the Rights of the Child's requirement to include young children in decision‐making. In the context of ongoing discussion about young children's capacity to share their views and opinions about matters affecting them ...
Laura Lundy, Colette Murray, Kylie Smith, Carmel Ward   +3 more
wiley   +1 more source