Results 211 to 220 of about 124,493 (301)

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

A link between increased temperature and avian body condition in a logged tropical forest

open access: yesConservation Biology, EarlyView.
Abstract The combined effects of anthropogenic disturbances, such as logging and climate change, remain poorly understood; yet, they are the main threats to tropical biodiversity. Most tropical African countries lack long‐term climate data, so climate impacts on biodiversity cannot be assessed.
Moreen Uwimbabazi   +7 more
wiley   +1 more source

Overlap of nonbreeding wandering albatrosses with fisheries and implications for colony‐specific population trajectories at South Georgia

open access: yesConservation Biology, EarlyView.
Abstract Bycatch in fisheries is one of the most serious threats to pelagic seabirds, causing major population declines. Mitigation measures can reduce bycatch substantially, but many fisheries fail to apply best practices, and seabird mortality remains high.
V. Warwick‐Evans   +2 more
wiley   +1 more source

Regional and Sexual Dimorphism in Murine Skeletal Responses to Osteocytic HIF Pathway Modulation. [PDF]

open access: yesJ Orthop Res
Mendoza SV   +6 more
europepmc   +1 more source

Sex‐specific differences in the prevalence of intermediate hyperglycaemia states: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
There are sex‐specific disparities in the prevalence of different isolated intermediate hyperglycaemic states, which, in the context of clinical guidance to use FPG or HbA1c for identification, may contribute to underdiagnosis and undertreatment in primary care and introduce ascertainment bias into research and policy. Abstract Aims To evaluate the sex‐
Louise Cooper   +4 more
wiley   +1 more source

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li   +9 more
wiley   +1 more source

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