Results 21 to 30 of about 41,015 (216)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sexual dysfunction in the climacteric period and associated factors
Objectives: to evaluate associated factors with sexual dysfunction among middle-aged women. Methods: cross-sectional and analytical study was carried out with climacteric women attended at a Family Health Strategy Unit in the city of Montes Claros, MG ...
Jaqueline Teixeira Teles Gonçalves +5 more
doaj +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Purpose: Sexuality is very important for men’s health. Currently, phosphodiesterase type 5 inhibitors (PDE5i) remain the firstline therapy for erectile dysfunction, and no other oral drugs or drinks are approved and used clinically to treat male libido
Masato Shirai +9 more
doaj +1 more source
Study of Sexual Dysfunction among Females with Combined Oral Contraception [COC] versus Intrauterine Hormonal Device [PDF]
Background: Sexuality in females is a multidimensional issue of psychological, physiological and cultural components. Evaluation of sexual partner, intimate relationships, and past abusive relationships or sexual trauma is crucial in female sexual ...
Alaa Talaat, Abdelraouf Oun, Waleed Ayad
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Addressing Sexual Health in Oncology Patients
N/a.
Margarida Alves +2 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Prescripción de Sildenafil en el policlínico docente "Manuel Fajardo Rivero"
Fundamento: la sexualidad es ampliamente aceptada como una parte importante e integral del bienestar físico y emocional, un marcador del estado de salud y la calidad de vida del paciente.
Sarah María Regueira Betancourt +3 more
doaj
Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology
Sexual and gonadal dysfunction/infertility are quite common in patients with chronic kidney disease. Forty percent of male and 55% of female dialysis patients do not achieve orgasm. The pathophysiology of gonadal dysfunction is multifactorial.
Manish Rathi, Raja Ramachandran
doaj +1 more source

