Results 221 to 230 of about 1,954,687 (382)

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

Sexual dysfunction in women with breast cancer: a systematic review. [PDF]

open access: yesSupport Care Cancer
Rodrigues-Machado N   +5 more
europepmc   +1 more source

The Management of Neurogenic Bladder and Sexual Dysfunction After Spinal Cord Injury

open access: bronze, 2001
Anthony S. Burns   +2 more
openalex   +1 more source

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

open access: yesAdvanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar   +10 more
wiley   +1 more source

Sexual dysfunction in women with genital warts: a cross-sectional study. [PDF]

open access: yesBMC Womens Health
Zaky MS   +4 more
europepmc   +1 more source

Sexual dysfunction following rectal cancer surgery

open access: yesInternational Journal of Colorectal Disease, 2017
Valerio Celentano   +4 more
semanticscholar   +1 more source

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy