Results 271 to 280 of about 1,691,927 (401)

Symptoms of sexual dysfunction in men with chronic patient patial syndrome / chronic prostatit of III type and depression

, 2018
M. N. Kryuchkova, A. Ya. Perechov
openalex   +2 more sources

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Sexual dysfunction and quality of life in males with genital warts. [PDF]

Basic Clin Androl
Elhamady MM, Atallah RB, Hashem OA, Abdelaty MA, Elsaie ML.   +4 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Clinical practice guidelines: sexual dysfunction in gynecological cancer patients. [PDF]

Sex Med
Peleg Nesher S, Luria M, Sartorius G, Tripodi F, Lew-Starowicz M, Both S, Maseroli E, Reisman Y, Corona G.   +8 more
europepmc   +1 more source

What is the comparative effectiveness of cognitive behavioral therapy versus medical treatment in improving sexual function for women with sexual dysfunction?

Yunike Putri Nurfauzia, Indriyani Wijaya, Mutia Juliana, Yahya Nurlianto   +3 more
openalex   +2 more sources

Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors

, 2007
David Asboe, J. Catalan, Sundhiya Mandalia, Nikos Dedes, Éric Florence, Ward Schrooten, Christiana Noestlinger, Robert Colebunders   +7 more
openalex   +2 more sources

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

A Narrative Review of the Roles of Nursing in Addressing Sexual Dysfunction in Oncology Patients. [PDF]

Curr Oncol
Alqaisi O, Al-Ghabeesh S, Tai P, Wong K, Joseph K, Yu E.   +5 more
europepmc   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source