From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Antidepressant-associated sexual dysfunction: impact, effects, and treatment
Agnes Higgins, Michael Nash, Aileen M LynchSchool of Nursing and Midwifery Studies, Trinity College Dublin, Dublin, IrelandAbstract: Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person’s ...
LYNCH, AILEEN +5 more
core +1 more source
Does post-acute COVID-19 syndrome women's sex problems link to psychiatry after 6 months?
Background Few data about women's sexuality practices post-acute COVID-19 syndrome are available. Many women who have had the disease experience sexual dysfunction; hence, the adverse effect of COVID-19 on sexual function has generated interest. We aimed
Rofaida Refaat Shehata +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Problems with sexual function in people attending London general practitioners: Cross sectional study [PDF]
Objectives: To assess sexual behaviour, prevalence of ICD-10 diagnosed sexual dysfunction, associations between sexual and psychological problems, and help seeking for sexual problems in people attending general practice; to assess predictors of ICD-10 ...
Nazareth, I, Boynton, P, King, M
core
The sexual excitation/sexual inhibition inventory for women: psychometric properties [PDF]
This is a post-print version of the article. The official published version can be found at the link below.This article reports on the development of a new questionnaire designed to assess the propensity for sexual excitation and sexual inhibition in ...
Milhausen, RR +5 more
core +1 more source
Introduction: Human T-lymphotropic virus (HTLV)-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disorder that mostly affects women.
Adenilda Lima Lopes Martins, MD, PhD +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Measuring sexual function in community surveys: development of a conceptual framework. [PDF]
Among the many psychometric measures of sexual (dys)function, none is entirely suited to use in community surveys. Faced with the need to include a brief and non-intrusive measure of sexual function in a general population survey, a new measure was ...
Kaye Wellings +4 more
core +1 more source
Sexual dysfunction in men seeking infertility treatment: The prevalence and associations
Introduction: Infertility is a major stressor in life and can cause disturbances in both sexual and marital relationships. Therefore, the objective of this study was to determine the frequency of sexual dysfunctions among infertile couples, who referred ...
Afsaneh Bakhtiari +2 more
doaj +2 more sources

