Results 101 to 110 of about 1,806,168 (389)

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for the conservative and nonpharmacological management of female pelvic floor dysfunction [PDF]

, 2016
There has been an increasing need for the terminology on the conservative management of female pelvic floor dysfunction to be collated in a clinically based consensus report.This Report combines the input of members and elected nominees of the ...
Abramov, Yoram, Almeida, Fernando G., Berghmans, Bary, Bo, Kari, Bortolini, Maria, Dumoulin, Chantale, Frawley, Helena C., Gomes, Mario, Haylen, Bernard T., McClurg, Doreen, Meijlink, Jane, Shelly, Elizabeth, Trabuco, Emanuel, Walker, Carolina, Wells, Amanda   +14 more
core   +3 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

The accuracy of the Arizona Sexual Experience Scale (ASEX) to identify sexual dysfunction in patients of the schizophrenia spectrum [PDF]

, 2009
BACKGROUND: Sexual dysfunction is frequent in patients with schizophrenia, it is reported as one of the most distressing antipsychotic's adverse effects and it is directly related to treatment compliance.
Bressan, Rodrigo Affonseca, Dieckmann, Luiz Henrique Junqueira, Lacaz, Fernando Sargo, Mari, Jair de Jesus, Matsuo, Tiemi, Nunes, Luciana Vargas Alves   +5 more
core   +4 more sources

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Correctional Change Through Neuroscience [PDF]

, 2016
Currently, the U.S. criminal justice system is under intense scrutiny. High- profile cases question the appropriateness of specific types of evidence, decision making in sentencing, and the treatment of convicted offenders.
Baskin-Sommers, Arielle R., Fonteneau, Karelle   +1 more
core   +1 more source

A narrative review on sexual wellbeing and dysfunctions: Research in the past 15 years

Indian Journal of Psychiatry
Background: Psychosexual health is an important aspect of mental and physical wellbeing. Though Indian culture has a rich history of sexuality, over the years, our population has been reticent in talking about the same.
Neena Sawant, Sreelakshmi Vaidyanathan, T S Sathyanarayana Rao, Suparna Telang   +3 more
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Asexuality: Classification and characterization [PDF]

, 2007
This is a post-print version of the article. The official published version can be obtaineed at the link below.The term “asexual” has been defined in many different ways and asexuality has received very little research attention.
A. Agmo, A. Bechara, A. F. Bogaert, A. Johnson, A. Riley, American Psychiatric Association, American Psychiatric Association, B. M. Alexander, B. N. Cuthbert, B. S. Mustanski, C. A. Hedricks, C. M. Steele, Cynthia A. Graham, D. A. Damassa, D. A. Strong, D. Bindra, D. Binson, D. J. Carlat, D. M. Green, E. Carmen, E. Cole, E. D. Rothblum, E. F. Hoon, E. F. Hoon, E. J. H. Meuleman, E. Janssen, Editors of the American Heritage Dictionaries, F. Montorsi, I. Spector, J. A. Gray, J. A. Vroege, J. Bancroft, J. Bancroft, J. D. Weinrich, J. G. Beck, J. H. Gray, J. M. Irvine, J. Rubin, J. S. Hyde, J. S. Hyde, K. A. Neuendorf, K. J. Zucker, L. Canin, L. F. O’Sullivan, L. M. Carpenter, L. M. Diamond, L. Schover, L. Zevy, M. Brezsnyak, M. Burisch, M. H. Birnbaum, M. S. Milligan, M. W. Ross, N. Haslam, Nicole Prause, P. S. Nurius, R. Basson, R. Green, R. L. Sell, R. R. Alteneder, R. Whalen, S. A. Brown, S. Deacon, T. D. Giargiari, V. E. Stone, W. Everaerd, W. Portillo, Y. M. Binik   +67 more
core   +1 more source