Results 101 to 110 of about 13,171,067 (358)

Reduced treatment-emergent sexual dysfunction as a potential target in the development of new antidepressants [PDF]

open access: yes, 2013
Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being.
Masdrakis, V.G.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Female Sexual Function and Gestational Diabetes

open access: yes, 2012
Introduction. The number of women with gestational diabetes mellitus (GDM) is growing worldwide in parallel with the obesity epidemic. The diagnosis of GDM leads to substantial modifications in the daily routine of these women, and these adjustments ...
Mattar, Rosiane [UNIFESP]   +8 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

PS-01-012 Which biopsychosocial variables affect more level of sexual desire in men?

open access: yes, 2017
Literature showed a close relationship between desire and arousal on the female side, emphasized by the DSM-5. There is the need for better understanding the male sexual response which has historically been considered more simple and mechanistic compared
F. Tripodi   +7 more
core   +1 more source

Sexual health implications of Covid-19 pandemic

open access: yes, 2020
Introduction: A novel coronavirus (COVID-19) reached pandemic levels by March 11th, 2020, with a destructive impact across socioeconomic domains and all facets of global health, but little is known of its impact on sexual health.
Jatoi, Noor-Ahmed   +8 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Developing and Validating a Taiwan Version of the Female Sexual Function Index for Pregnant Women

open access: yes, 2010
INTRODUCTION: Health professionals should pay more attention to the sexual concerns of pregnant women. An assessment instrument for female sexual function is needed for pregnant women in the Taiwanese population.
CHANG, SHIOW-RU;CHANG, TING-CHEN;CHEN, KUANG-HO;LIN, HO-HSIUNG   +1 more
core  

Does Infertility Affect the Sexual Function and Sexual Quality of Life of Women? A Case Control Study

open access: yes, 2020
Objectives: The study aimed to determine the effect of infertility on women's sexual function and sexual quality of life. Methods: In this case-control study, 316 infertile and 316 fertile women were interviewed in a hospital using the Index of ...
POTUR, DİLEK, DEMİRCİ, NURDAN
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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