Results 131 to 140 of about 13,171,067 (358)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Sexual Function and Sexual Behavior in Women with Breast Cancer Having Sexual Distress, Zanjan, Iran [PDF]

Preventive Care in Nursing and Midwifery Journal, 2017
Background: Sexual relationships of women with breast cancer are affected by diagnostic and therapeutic procedures. Objectives: The aim of this study was to assess sexual function and sexual behavior in women with breast cancer having sexual distress in
Esmkhani M, Kharaghani R, Merghaty Khoie E, Faghihzadeh S, Shakibazadeh E   +4 more
doaj  

The sexual excitation/sexual inhibition inventory for women: psychometric properties

, 2006
This is a post-print version of the article. The official published version can be found at the link below.This article reports on the development of a new questionnaire designed to assess the propensity for sexual excitation and sexual inhibition in ...
Milhausen, RR, Sanders, Stephanie A., Milhausen, Robin R., Sanders, SA, Graham, CA, Graham, Cynthia A.   +5 more
core   +1 more source

Methodology of the third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3). [PDF]

, 2013
BACKGROUND: Data from the first two National Surveys of Sexual Attitudes and Lifestyles, carried out in 1990-1991 (Natsal-1) and 1999-2001 (Natsal-2), have been extensively used to inform sexual health policy in Britain over the past two decades.
Clare Tanton, Kaye Wellings, Catherine H Mercer, Mitchell, K., Johnson, A. M., Erens, Bob, Hussey, D., Copas, AJ, Sonnenberg, Pam, David Hussey, Tanton, Clare, Datta, J., Macdowall, W, Sonnenberg, P, Phelps, Andrew, Wellings, K., Anne M Johnson, Clifton, S., Johnson, Anne M, Field, N., Mercer, C. H., Tanton, C, Jessica Datta, Wellings, K, Macdowall, W., Pam Sonnenberg, Hussey, David, Mercer, CH, Erens, B., Macdowall, Wendy, Field, N, Phelps, A., Datta, J, Datta, Jessica, Wendy Macdowall, Kirstin Mitchell, Mercer, Catherine H, Copas, Andrew J, Tanton, C., Phelps, A, Johnson, AM, Field, Nigel, Erens, B, Mitchell, K, Sonnenberg, P., Wellings, Kaye, Mitchell, Kirstin, Hussey, D, Andrew Phelps, Soazig Clifton, Copas, A. J., Nigel Field, Andrew J Copas, Bob Erens, Clifton, S, Clifton, Soazig   +55 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Translational Perspective on the Role of Testosterone in Sexual Function and Dysfunction

Journal of Sexual Medicine, 2016
Introduction The biological importance of testosterone is generally accepted by the medical community, however controversy focuses on its relevance to sexual function and the sexual response, and our understanding of the extent of its role in this area ...
C. Podlasek, J. Mulhall, K. Davies, C. Wingard, J. Hannan, T. Bivalacqua, B. Musicki, M. Khera, N. Gonzalez-Cadavid, A. Burnett   +9 more
semanticscholar   +1 more source

Assessment of Sexual Function in Women with Polycystic Ovary Syndrome. [PDF]

Al-Azhar International Medical Journal
Background: Polycystic Ovary Syndrome is a frequently occurring endocrine condition impacting a notable proportion of women of childbearing age, with estimates spanning from 8% to15% of this population.
Nada Ghozy, Hassan Abou Khodair Mohamed, Ramadan Eldhshan, Mohamed Thabet   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source