Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia+20 more
wiley +1 more source
Transdermal Testosterone Gel Improves Sexual Function, Mood, Muscle Strength, and Body Composition Parameters in Hypogonadal Men1 [PDF]
Christina Wang+8 more
openalex +1 more source
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad+15 more
wiley +1 more source
Female Sexual Function Index questionnaire must not be used to assess female sexual function
Vincenzo Puppo
doaj +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
Fatigue, sexual function and mood following treatment for haematological malignancy: the impact of mild Leydig cell dysfunction [PDF]
Sacha J. Howell+3 more
openalex +1 more source
Circulating Interleukin‐6 Levels and Timing of Acute Ischemic Stroke Onset
ABSTRACT Intravenous thrombolysis is the most widely available effective ischemic stroke treatment, but is approved only if given within 4.5 h from stroke onset. Many patients are not treated because stroke onset time is unknown. We evaluated the cytokine interleukin 6 (IL‐6) in circulating blood after acute ischemic stroke (AIS).
Robert G. Kowalski+15 more
wiley +1 more source
Editorial: Sexual function and dysfunction in men and women with diabetes. [PDF]
Coppola A, Esposito K, Gazzaruso C.
europepmc +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay+12 more
wiley +1 more source
Sexual function, depression, and quality of life in patients with irritable bowel syndrome. [PDF]
Keshavarzi A+4 more
europepmc +1 more source