Results 71 to 80 of about 1,037,157 (361)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Prevalence and associated risk factors for sexual dysfunction among postmenopausal women: a study from Iran

open access: yesWomen's Midlife Health, 2021
Background Female Sexual Dysfunction (FSD) is a distressing condition linked to menopause. This study aimed to determine the prevalence and contributing factors for FSD among postmenopausal women. Methods This was a cross-sectional study.
Azadeh Tavoli   +3 more
doaj   +1 more source

Sexual Dysfunction as a Side Effect of Hyperprolactinemia in Methadone Maintenance Therapy [PDF]

open access: yes, 2013
Although endocrine abnormalities are recognized in opiate users, very little is known about the range of hormones affected, their pathophysiology and their clinical relevance.
Spasovska Trajanovska, Aneta   +4 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

The effect of sexual health literacy on sexual function mediated by sexual satisfaction and sexual self-efficacy: Structural equation modeling approach.

open access: yesPLoS ONE
Existing literature suggests that sexual health literacy may influence sexual function by enhancing sexual satisfaction and other dimensions of sexual health.
Mojdeh Banaei   +6 more
doaj   +1 more source

Multi-agent system for dynamic manufacturing system optimization [PDF]

open access: yes, 2008
This paper deals with the application of multi-agent system concept for optimization of dynamic uncertain process. These problems are known to have a computationally demanding objective function, which could turn to be infeasible when large problems are ...
A.J. Gonzalez   +6 more
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Correlation of Sexual Knowledge and Attitude with Sexual Function in Female Nurses

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: Healthy and satisfying sexual life is one of the important elements of welfare in women and their quality of life. In this study, the correlation of sexual knowledge and attitude with sexual function in female nurses, was ...
Bita Shalani, Rahele Siyahkamari
doaj  

The Relationship between Sexual Self-concept and Sexual Function in Women of Reproductive Age Referred to Health Centers in Gorgan, North East of Iran [PDF]

open access: yesJournal of Midwifery & Reproductive Health, 2017
Background & aim: The preservation and enhancement of the sexual function are the key elements of sexual health. One of the most important predictive factors of sexual behavior and function is sexual self-concept.
Tayebe Ziaei   +3 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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