Results 81 to 90 of about 1,255,549 (254)

Who goes to a sexual health clinic? Gender differences in service utilisation. [PDF]

, 2008
Aim: Our aim was to review utilisation of the Hamilton Sexual Health Clinic (Hamilton, Waikato, New Zealand) with regard to gender differences. Methods: Notes of those attending during 9 months (1 February 2008–31 October 2008) were reviewed—and their
Haar, Jarrod M., Morgan, Jane
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Cost‐effectiveness of screening for anal cancer using regular digital ano‐rectal examinations in men who have sex with men living with HIV

Journal of the International AIDS Society, 2016
Introduction Anal cancer in men who have sex with men (MSM) living with HIV is an important issue but there are no consistent guidelines for how to screen for this cancer.
Jason J Ong, Christopher K Fairley, Susan Carroll, Sandra Walker, Marcus Chen, Tim Read, Andrew Grulich, Catriona Bradshaw, John Kaldor, Philip Clarke   +9 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

ABC of sexual health: Sexual variations

BMJ, 1999
“Sexual variations” refer to sexual desires and behaviours outside what is considered to be the normal range, although what is unusual or atypical varies between cultures and from one period to another. Defining normality is extremely difficult (and arbitrary), because the definition involves making a value judgment and therefore labelling how we view ...
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Growing inequities by immigration group among older adults: population-based analysis of access to primary care and return to in-person visits during the COVID-19 pandemic in British Columbia, Canada

BMC Primary Care
Background The onset of the COVID-19 pandemic drove a rapid and widespread shift to virtual care, followed by a gradual return to in-person visits. Virtual visits may offer more convenient access to care for some, but others may experience challenges ...
Cecilia Sierra-Heredia, Elmira Tayyar, Yasmin Bozorgi, Padmini Thakore, Selamawit Hagos, Ruth Carrillo, Stefanie Machado, Sandra Peterson, Shira Goldenberg, Mei-ling Wiedmeyer, M Ruth Lavergne   +10 more
doaj   +1 more source

Availability, acceptability and adoption of decision aids for HIV prevention and contraception for young people: a scoping review protocol

BMJ Open
Introduction Young people face challenges in accessing information on HIV and sexual and reproductive health services, with corresponding suboptimal uptake. Decision aids can provide information and decisional support to improve young people’s engagement
Collin Mangenah, Euphemia Sibanda, Itai Kabonga, Oppah Kuguyo, Lindiwe Mancitshana, Kudzai Chidhanguro, Sharon Munhenzva, Fadzai Masiyambiri, Nancy Ruhode   +8 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source