Results 121 to 130 of about 977,125 (259)

Gender differences in factors associated with sexual intercourse among Estonian adolescents

, 2011
Aims: To examine factors associated with early sexual intercourse among 15 to 16-year-old adolescents by gender. Methods: The data were collected from a random sample of Estonian basic schools’ ninth grade pupils in 1999 using self-completed ...
Mati Rahu, Helle Karro, Kai Part, Kaja Rahu   +3 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A qualitative study of heterosexual women's attempts to renegotiate sexual relationships in the context of severe sexual problems

, 2012
Previous qualitative research on women's sexual problems has documented the ways in which they can impact psychological well-being as well as women's close interpersonal relationships.
Wylie, K, Hinchliff, S, Gott, M
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Race, Ethnicity, Substance Use, and Unwanted Sexual Intercourse among Adolescent Female in the United States

Western Journal of Emergency Medicine, 2012
Introduction: The purpose of this study was to examine racial/ethnic disparities in being forced to have sexual intercourse against one’s will, and the effect of substance use on these disparities.Methods: We analyzed data from adolescent women ...
Nancy J. Thompson, Darren Mays, Robin E. McGee   +2 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Sexual and mental health disparities among young sexual minority women compared to exclusively heterosexual women: a national study

Frontiers in Global Women's Health
IntroductionYoung sexual minority women (YSMW)'s sexual health is often overlooked in research, with most studies focusing on men who have sex with men or transgender women.MethodsThis study compares the sexual and mental health of young lesbians and ...
Diana Fernandes, Lorraine Chok, Camille Béziane, Yara Barrense-Dias   +3 more
doaj   +1 more source

Trajectory of unprotected sexual intercourse over 3 years among HIV patients in Tanzania.

, 2013
Trajectory of unprotected sexual intercourse over 3 years among HIV patients in Tanzania.
Kathryn Whetten (255678), Kristen G. Shirey (499205), Rachel Whetten (319502), Dafrosa Itemba (323338), Venance Maro (467026), Jia Yao (323339), Brian W. Pence (255687), Nathan M. Thielman (231240)   +7 more
core   +1 more source