Results 51 to 60 of about 247,698 (307)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The epidemiology of sexually transmitted infections in the United Kingdom: impact of behaviour, services and interventions [PDF]

open access: yes, 2015
Sexually transmitted infections (STIs) are a major public health concern. The United Kingdom (UK) has some of the most advanced STI surveillance systems globally.
Field, NM, Hughes, G
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Interprofessionalism as a driver for professional nursing education aimed at comprehensive care for sexual and gender minorities by 2030 [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to reflect on the contribution of interprofessional education in nursing to the comprehensive care of sexual and gender minorities, aligned with the Sustainable Development Goals (SDGs) of the 2030 Agenda.
Gabriela Rodrigues Bragagnollo   +3 more
doaj   +1 more source

Determinants of body image disturbance and disordered eating behaviors among self-identified LGBTQ individuals

open access: yesJournal of Eating Disorders, 2023
It has been previously established that sexual minorities are more likely to suffer from mental health illnesses due to experiencing unique stressors such as fear, anxiety, stigma, harassment, and prejudice.
Nour Kalash   +4 more
doaj   +1 more source

The association of sexual orientation with allostatic load and cardiovascular health: An analysis of the National Health and Nutrition Examination Survey (NHANES) [PDF]

open access: yes, 2020
Background: Cardiovascular disease (CVD) is an important health problem among sexual minorities given increased stress, according to minority stress theory.
Louden, Elaine
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Evaluating Respiratory Sinus Arrhythmia as a Mediator of Relations between Minority Stress and Depressive Symptoms Among Sexual Minorities [PDF]

open access: yes, 2020
Compared with heterosexuals, those with sexual minority identities (e.g., lesbian, gay, bisexual) are at significantly greater risk of psychopathology, including depression—the most common mental health disorder in the general population. A large body of
Mustafa, Jazmyn
core  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy