Results 141 to 150 of about 92,989 (309)
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi +5 more
wiley +1 more source
Manipulating Unisexual-Sexual Reproduction Transition to Engineer Genome-Reconstructed Polyploids. [PDF]
Lu M +9 more
europepmc +1 more source
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian +5 more
wiley +1 more source
Editorial: Meiosis in plants: sexual reproduction, genetic variation and crop improvement. [PDF]
Wang Y, Chen C, Copenhaver GP, Wang CR.
europepmc +1 more source
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol +17 more
wiley +1 more source
The effects of biotic stress on the sexual reproduction process of flowering plants. [PDF]
Li Z +6 more
europepmc +1 more source
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Sexual reproduction in land plants: an evolutionary perspective. [PDF]
Becker A +8 more
europepmc +1 more source

