Results 151 to 160 of about 1,874,469 (397)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

HORMONAL CONTROL OF SEXUAL REPRODUCTION IN MUCOR MUCEDO [PDF]

, 1968
G. W. Gooday
openalex   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

Correction to: ASRHR in Ethiopia: reviewing progress over the last 20 years and looking ahead to the next 10 years

Reproductive Health, 2022
Elsie Akwara, Kereta Worknesh, Lemessa Oljira, Lulit Mengesha, Mengistu Asnake, Emiamrew Sisay, Dagem Demerew, Marina Plesons, Wegen Shirka, Azmach Hadush, Venkatraman Chandra-Mouli   +10 more
doaj   +1 more source

STRIPAK complex defects result in pseudosexual reproduction in Cryptococcus neoformans.

PLoS Genetics
STRIPAK is an evolutionarily conserved signaling complex that coordinates diverse cellular processes across fungi and animals. In the human fungal pathogen Cryptococcus neoformans, STRIPAK was recently shown to play critical roles in maintaining genome ...
Patricia P Peterson, Sarah Croog, Yeseul Choi, Sheng Sun, Joseph Heitman   +4 more
doaj   +1 more source

Body size and clonality consequences for sexual reproduction in a perennial herb of Brazilian rupestrian grasslands

Brazilian Journal of Biology
Body size is one of the most important factors regarding herbaceous perennial plants life-histories, and several fitness components of these organisms are related to size.
GR Demetrio, FF Coelho, MEA Barbosa
doaj   +1 more source

History and prospects of plant sexual reproduction congresses, the IASPRR and sexual plant reproduction [PDF]

, 2008
Willemse, M.T.M.
core   +2 more sources

Elevated temperature changes female costs and benefits of reproduction [PDF]

, 2018
Despite obvious benefits, reproduction also imposes severe costs on females. Such costs and benefits are highly sensitive to environmental factors. Rapidly changing conditions may thus disturb a finely poised balance between the two and pose a challenge ...
Grazer, Vera, Martin, Oliver
core  

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

Advanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai, Xue Zhou, Yu Zhuang, Lian Cui, Rui Ma, Youdong Chen, Nan Yang, Qianyu Chen, Yuanyuan Wang, Peiyao Zhu, Lingling Yao, Qian Yu, Xiaomin She, Xuyang Zhou, Yuemeng Huang, Zengyang Yu, Xilin Zhang, Jiajing Lu, Yuling Shi, Chunyuan Guo   +19 more
wiley   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source