RPS27L Enhances Myogenesis and Muscle Mass by Targeting IGF1 Through Liquid‐Liquid Phase Separation
Muscle‐specific RPS27L knock‐in mice exhibit increased body weight, muscle mass, and enhanced muscle regenerative capacity. RPS27L drives myogenesis by promoting myoblast proliferation, while inhibiting myogenic differentiation. Mechanistically, RPS27L targets IGF1 protein by liquid‐liquid phase separation through its N‐terminal intrinsically ...
Xiaoqin Liu +17 more
wiley +1 more source
Lack of successful sexual reproduction suggests the irreversible parthenogenesis in a stick insect. [PDF]
Nozaki T +5 more
europepmc +1 more source
Evolution is driven by natural autoencoding: reframing species, interaction codes, cooperation and sexual reproduction. [PDF]
Cohen IR, Marron A.
europepmc +1 more source
Sexual reproduction in field populations of the facultative apomict,Hieracium pilosella [PDF]
Gary J. Houliston, Hazel Chapman
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Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai +7 more
wiley +1 more source
Transcription factor-dependent regulatory networks of sexual reproduction in Fusarium graminearum. [PDF]
Kim W +5 more
europepmc +1 more source
Invasion success of a Lessepsian symbiont-bearing foraminifera linked to high dispersal ability, preadaptation and suppression of sexual reproduction. [PDF]
S Raposo D +7 more
europepmc +1 more source
Severely reduced sexual reproduction in northern populations of a clonal plant, Decodonverticillatus (Lythraceae) [PDF]
Marcel E. Dorken, Christoper G. Eckert
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YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li +10 more
wiley +1 more source

