Results 61 to 70 of about 78,202 (153)

Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew   +6 more
wiley   +1 more source

Sedimentary chydorid (Cladocera) ephippia in relation to lake ecological quality in the Austrian Alps

open access: yesJournal of Limnology, 2013
Research on chydorid (Crustacea: Cladocera: Chydoridae) reproduction is scarce and very little is known about the dynamics of parthenogenetic (asexual) and gamogenetic (sexual) reproduction modes in these cyclical parthenogens.
Liisa Nevalainen, Tomi Petteri Luoto
doaj   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain

open access: yesAdvanced Science, EarlyView.
This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li   +17 more
wiley   +1 more source

Viewpoints on apornictic and sexual reproduction in angiosperms

open access: yesActa Societatis Botanicorum Poloniae, 2014
Gametophytic apomixis implies different changes of the reproductive cycle of sexual plants. Each of these "elements of apomixis" occurs in sexual plants, which may even display functional diploid parthenogenesis.
Sven Asker
doaj   +1 more source

NF2 is Essential for Human Endoderm Development

open access: yesAdvanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong   +5 more
wiley   +1 more source

Gut Microbiota Modulation by Inulin Improves Metabolism and Ovarian Function in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng   +8 more
wiley   +1 more source

Protocol to assess bottlenecks inhibiting the scaling up of evidence-based family planning practices in low-income and middle-income countries using mixed methods

open access: yesBMJ Open
Introduction Scaling up evidence-based practices (EBPs) in family planning (FP), as recommended by the WHO, has increasingly been accepted by global health actors as core to their mission, goals and activities.
James Kiarie   +6 more
doaj   +1 more source

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