Results 111 to 120 of about 3,837 (260)

Exploring and Explaining the Use and Proliferation of Whole Life Orders in England and Wales

The Howard Journal of Crime and Justice, EarlyView.
ABSTRACT Whole life orders (WLOs) represent the power of the state to inflict harm at its most extreme, with such sentences being found to be in breach of the European Convention on Human Rights. However, very little research has endeavoured to understand the use of WLOs.
Hannah Gilman, Jake Phillips
wiley   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

Somerset Maugham's Failings

Critical Quarterly, EarlyView.
Allan Hepburn
wiley   +1 more source

Implementation of the ‘Countdown to Theatre’ Approach to Bridge the Evidence–Practice Gap in Paediatric Preoperative Fasting: A Quality Improvement Initiative

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate the ‘Countdown to Theatre’ intervention, a co‐designed nurse‐led approach developed using the COM‐B framework to address context‐specific barriers and facilitators to preoperative fasting practices. Design A prospective mixed‐method, pre–post study assessed the intervention's impact on fasting adherence and patient experience ...
Erika Dulay, Bronwyn Griffin, Du Trung, Craig A. Mcbride, Adrienne P. Hudson, Diana Hermith‐Ramirez, Amanda J. Ullman   +6 more
wiley   +1 more source

The History of the Panmictic Population Concept and Its Legacy in Contemporary Population Genetics. [PDF]

Ann Hum Genet
Walton A, Aylward A, Thomas MG, Rutherford A.   +3 more
europepmc   +1 more source

Genetic Evaluation of Beef Sires Using a Beef‐on‐Dairy Crossbred Reference Population

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In recent years, Beef‐on‐Dairy (BoD) crossbreeding programs have gained momentum to enhance dairy cattle's economic and genetic merits while meeting the demand for high‐quality beef. However, bulls with superior growth potential can lead to calving problems; thus, Holstein dairy farmers must decide which semen to use to avoid calving problems ...
Julius Mugambe, Christin Schmidtmann, Jorge Hidalgo, Rana Ahmed, Georg Thaller   +4 more
wiley   +1 more source

Genomic evidence for a-α heterothallic and α-α unisexual mating and recombination in an environmental Cryptococcus deneoformans population. [PDF]

PLoS Genet
Hitchcock M, Thorn V, Samarasinghe H, Sun S, Heitman J, Xu J.   +5 more
europepmc   +1 more source

Impact of Model Parameterisation and Variance Component Estimates on Genomic Predictions of Carcass Traits in Montana Composite Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT This study evaluated the influence of variance component (VC) estimates, obtained from different models and two relationship matrices, pedigree‐based (BLUP) and genomic information‐based (ssGBLUP), on genomic predictions of carcass traits in Montana composite cattle.
Caroline Assis Almeida, Felipe Eguti de Carvalho, Flávia Cristina Bis, Rachel Santos Bueno Carvalho, Elisângela Chicaroni de Mattos, Rafael Espigolan, Joanir Pereira Eler, Luís Telo da Gama, Fernando Baldi, José Bento Sterman Ferraz   +9 more
wiley   +1 more source

RNAi epimutations conferring antifungal drug resistance are inheritable. [PDF]

Nat Commun
Pérez-Arques C, Navarro-Mendoza MI, Xu Z, Walther G, Heitman J.   +4 more
europepmc   +1 more source

Genomic Prediction Ability Using Linear and Threshold Approaches for Different Stayability Definitions in Nellore Females

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Enhancing female longevity through regular calvings improves herd replacement rates and reduces the costs associated with replacing low reproductive efficiency animals. Stayability (STAY), defined as a cow's ability to remain productive in the herd, is a categorical trait that challenges traditional genetic evaluation due to its non‐normal ...
Letícia Silva Pereira, Larissa Bordin Temp, Eduarda da Silva Oliveira, Jorge Hidalgo, Cláudio Ulhoa Magnabosco, Fernando Baldi   +5 more
wiley   +1 more source