Results 181 to 190 of about 373,888 (262)

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

Activism as a long durée journey: Teachers against the Chilean neoliberal education model

British Educational Research Journal, EarlyView.
Abstract In this paper, I use the idea of purposes of education, particularly subjectification, and the concept of love to explore long‐term teacher activism in Chile. ‘Long‐term activism’ is used to describe an ongoing struggle rather than activism confined to specific moments.
Carla Tapia‐Parada
wiley   +1 more source

The absent presence of disability in British higher education

British Educational Research Journal, EarlyView.
Abstract Rates of disability disclosure are steadily increasing in British higher education (HE), with 18% of the student population having a known disability in 2023/24. It might be assumed that progress is being made with increased representation, rights and support for disabled students.
G. Koutsouris, L. Stentiford, E. Dimitrellou, Z. Yu, Pujaningsih, N. Azizah   +5 more
wiley   +1 more source

Pathways to employment: Subject choice, job requirements, and early employment outcomes for UK undergraduates

British Educational Research Journal, EarlyView.
Abstract Higher education in the United Kingdom has dramatically expanded in recent decades, along with questions about its effectiveness in preparing graduates for the labour market. With rising tuition fees and increasing competition for graduate jobs, many students opt to study ‘professional’ subjects—fields closely tied to specific professions ...
Sarah Pemberton
wiley   +1 more source

International student agency in academic self‐formation: Mobility as agency situated within knowledge structures

British Educational Research Journal, EarlyView.
Abstract With growing attention to student agency in academic and policy discourse, international education has become a prominent context for examining how students navigate new cultural, academic, linguistic and social environments. However, much of this discussion attributes student agency to the ‘international’ aspect, while overlooking the ...
Soyoung Lee
wiley   +1 more source

Technology‐enhanced learning in higher education institutions: Exploring the lived experiences of students with specific learning differences and their lecturers

British Educational Research Journal, EarlyView.
Abstract This paper challenges the prevailing assumption that technology‐enhanced learning (TEL) inherently benefits all students in higher education, examining how undergraduate students with specific learning differences (SpLDs) and/or autism spectrum disorder (ASD) use technology for learning.
Alexia Achtypi, Abass B. Isiaka, Jeremy Schildt, Fabio Arico   +3 more
wiley   +1 more source

Green Human Resource Management and Employee Green Behaviour in Hotels: Mediating Roles of Job Satisfaction and Work Well‐Being

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates the impact of green human resource management (GHRM) practices on employee green behavioural intention (GBI) and in‐role green behaviour (EGB‐IR) in the hospitality sector. Drawing on conservation of resources (COR) theory, we examine the mediating roles of job satisfaction and employee well‐being as psychological ...
Vanessa Guerra‐Lombardi, Desiderio Gutiérrez‐Taño, Raúl Hernández‐Martín, Noemi Padrón‐Fumero   +3 more
wiley   +1 more source