Results 221 to 230 of about 221,310 (303)

Comparative functional analyses of the prostate-specific KLK3 enzyme in primates reveal the impact of sexual selection. [PDF]

Evolution
Kahveci EF, Colvin Zielen AM, Gibbs WJ, McIntyre CA, Modi R, Johnstonbaugh HZ, Washington TH, Brown DR, Hockman MR, Rossman NR, Jensen-Seaman MI.   +10 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Phylogenetic Relationships of Immune Function and Oxidative Physiology With Sexual Selection and Parental Effort in Male and Female Birds. [PDF]

Ecol Evol
Pap PL, Vágási CI, Bókony V, Pénzes J, Szabó K, Magonyi NM, Czirják GÁ, Vincze O.   +7 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Wing Membrane Thickness, Allometric Scaling and Wing Interference Patterns in Damselflies - A Target of Sexual Selection?

Li M, Tsuboi M, Runemark A, Svensson EI, Brydegaard M.   +4 more
europepmc   +1 more source

The correlation between anisogamy and sexual selection intensity-the broad theoretical predictions. [PDF]

Evol Lett
Lehtonen J, Parker GA.
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Natural Variation in Sexual Traits and Gene Expression between Selfing and Outcrossing Arabidopsis lyrata Suggests Sexual Selection at Work. [PDF]

Plant Cell Physiol
İltaş Ö, Čertner M, Lafon Placette C.   +2 more
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

A male-biased sex ratio increases the opportunity for precopulatory sexual selection but does not change the Bateman gradient. [PDF]

Evol Lett
McDonald GC, Edmunds D, Morimoto J, Wigby S, Perry JC.   +4 more
europepmc   +1 more source