Results 111 to 120 of about 3,300,887 (297)

Symmetry Is Related to Sexual Dimorphism in Faces: Data Across Culture and Species [PDF]

, 2008
Summary Background Many animals both display and assess multiple signals. Two prominently studied traits are symmetry and sexual dimorphism, which, for many animals, are proposed cues to heritable fitness benefits.
Marlow, Frank W., Jones, Benedict C, Perrett, David I., Feinberg, D.R., Waitt Corri, Jones, Benedict Christopher, Anthony C Little, David I Perrett, Waitt, Corri, Tiddeman, Bernard Paul, Coren L Apicella, Marlowe, Frank W, Apicella Coren L., Little, Anthony Charles, Corri Waitt, Apicella, Coren L, Marlowe, F.W., Apicella, Coren, Little, Anthony C., Little Anthony C., Waitt, C., Feinberg David R., Tiddeman, Bernard P., Jones, B.C., Feinberg, David Russell, Apicella, C.L., Little, Anthony, Perrett, David I, Marlowe Frank W., Feinberg, David R., Tiddeman Bernard P., Marlowe, Frank W., Benedict C Jones, Bernard P Tiddeman, Feinberg, David R, Apicella, Coren L., Tiddeman, Bernard P, David R Feinberg, Perrett David I., Apicella, C.A., Jones, Benedict C., Frank W Marlowe, Little, Anthony C, Perrett, D.I., Jones Benedict C., Tiddeman, B.P., Perrett, David Ian, Little, A.C.   +47 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Sexual Selection in a Brentid Weevil [PDF]

Evolution, 1982
In most insects, differences between the sexes involve not only primary characters necessary for gamete production, copulation, and oviposition, but also sexual structures and behaviors involved in the acquisition of mates. The most striking of these secondary characters, such as exaggerated size, weaponry, or coloration, tend to occur in males, and ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Handicap Principle in Sexual Selection [PDF]

Evolution, 1978
The theory of the selection of epigamic color, structure and behavior was originally due to Darwin (1874) and was later elaborated by Fisher (1930) and by O'Donald (1962, 1963, 1967). It is well known and is discussed below. An alternative account of this type of sexual selection has been suggested recently by Zahavi (1975).
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Sexual selection protects against extinction [PDF]

, 2019
Reproduction through sex carries substantial costs, mainly because only half of sexual adults produce offspring1. It has been theorized that these costs could be countered if sex allows sexual selection to clear the universal fitness constraint of ...
Kitson, James J. N., Morrison, Catriona A., Martin, Oliver Y., Spurgin, Lewis G., Gage, Matthew J. G., Michalczyk, Lukasz, Godwin, Joanne L., Lumley, Alyson J., Chapman, Tracey, Dickinson, Matthew E, Emerson, Brent C.   +10 more
core   +1 more source

Primate brain architecture and selection in relation to sex

BMC Biology, 2007
Background Social and competitive demands often differ between the sexes in mammals. These differing demands should be expected to produce variation in the relative sizes of various brain structures.
Nunn Charles L, Lindenfors Patrik, Barton Robert A   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source