Results 141 to 150 of about 7,111,434 (338)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Impacts of sperm competition on mating behaviour and life history traits in a simultaneous hermaphrodite [PDF]

open access: yes, 2013
Evolutionary theory suggests that post-copulatory sexual selection plays an important role in the evolution of reproductive traits of sexually reproducing animals.
Sandner, Peter
core   +1 more source

Sexual dimorphism in the South American water snake Helicops polylepis (Serpentes: Dipsadidae)

open access: yesPhyllomedusa: Journal of Herpetology, 2021
Sexual selection, fecundity selection and ecological divergence have been the main explanations proposed for the origin and maintenance of sexual dimorphism.
Isla Carol Marialva Camargo   +5 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Mating games: cultural evolution and sexual selection. [PDF]

open access: yes
In this paper, we argue that mating games, a concept that denotes cultural practices characterized by a competitive element and an ornamental character, are essential drivers behind the emergence and maintenance of human cultural practices.
Dewitte, Siegfried, De Block, Andreas
core  

Intra- versus inter-sexual selection in the dimorphic electric organ discharges of the snoutfish Marcusenius altisambesi (Mormyriformes, Teleostei) [PDF]

open access: yes, 2010
Marcusenius pongolensis (South Africa) and M. altisambesi (Upper Zambezi/Okavango) differ in the sex difference of their electric organ discharges (EODs). It is permanent and graded in the former and seasonally dimorphic in the latter.
Kramer, Bernd   +2 more
core   +1 more source

The origins and drivers of sexual size dimorphism in sharks

open access: yesEcology and Evolution
While sexual size dimorphism (SSD) is abundant in nature, there is huge variation in both the intensity and direction of SSD. SSD results from a combination of sexual selection for large male size, fecundity selection for large female size and ecological
Joel H. Gayford, Phillip C. Sternes
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Ecology, sexual selection and speciation

open access: yes, 2011
The spectacular diversity in sexually selected traits among animal taxa has inspired the hypothesis that divergent sexual selection can drive speciation.
Ole Seehausen   +3 more
core   +1 more source

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