The relationship between childhood trauma, personality, and subjective well-being in early and late adolescence: a network analysis. [PDF]
Zheng W, Zhou L, Lv X, Li J, Zhou Y.
europepmc +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
The psychological mechanism of Self-objectification: the interaction between sociocultural pressures and the self-system. [PDF]
Liu Z, Fu M, Shi J, Hu Y, Gao X.
europepmc +1 more source
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner +14 more
wiley +1 more source
"I Am Very Happy That We Are Such Beautiful People": Lived Experiences, Perceived Discrimination, and Mental Health in an LGBTIQ+ Community in Turkey. [PDF]
Kara B +4 more
europepmc +1 more source
Preaching, Teaching, and Living the Theology of the Body [PDF]
Cahall, Perry J.
core +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Moving Beyond Unintended Pregnancy: Development of a Person-Centered Conceptual Framework and Measure of Self-Assessed Pregnancy Acceptability. [PDF]
Borrero S +8 more
europepmc +1 more source
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi +11 more
wiley +1 more source

