Results 41 to 50 of about 487,907 (301)

An Update on Sexual Transmission of Zika Virus

Pathogens, 2018
Zika virus (ZIKV) is a single-stranded RNA virus belonging to the arthropod-borne flaviviruses (arboviruses) which are mainly transmitted by blood-sucking mosquitoes of the genus Aedes. ZIKV infection has been known to be rather asymptomatic or presented
Hercules Sakkas, Petros Bozidis, Xenofon Giannakopoulos, Nikolaos Sofikitis, Chrissanthy Papadopoulou   +4 more
doaj   +1 more source

Optimal control in a model for Zika transmission with stratification by sex

Selecciones Matemáticas, 2020
This paper presents an optimal control strategy for the Zika virus disease with sexual transmission. A mathematical model for the transmission of the Zika virus is considered with three preventive measures as control, namely: the prevention of the sexual
Erick Manuel Delgado Moya, Aymée Marrero Severo   +1 more
doaj   +1 more source

Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease. [PDF]

, 2018
Sexual transmission of Ebola virus (EBOV) has been demonstrated more than a year after recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying EBOV persistence and sexual transmission are not currently understood.
Bernbaum, John G., Hagen, Katie R., Holbrook, Michael R., Huzella, Louis M., Jahrling, Peter B., Johnson, Reed F., Perry, Donna L., Schnell, Matthias J.   +7 more
core   +1 more source

Prevention and control of Zika fever as a mosquito-borne and sexually transmitted disease

, 2016
The ongoing Zika virus (ZIKV) epidemic poses a major global public health emergency. It is known that ZIKV is spread by \textit{Aedes} mosquitoes, recent studies show that ZIKV can also be transmitted via sexual contact and cases of sexually transmitted ...
Chowell, G, Gao, D, He, D, Kuang, Y, Lou, Y, Porco, TC, Porco, Travis, Ruan, S   +7 more
core   +1 more source

Cellular and humoral immunity protect against vaginal Zika virus infection in mice [PDF]

, 2018
Zika virus (ZIKV), which can cause devastating disease in fetuses of infected pregnant women, can be transmitted by mosquito inoculation and sexual routes. Little is known about immune protection against sexually transmitted ZIKV.
Diamond, Michael S, Fernandez, Estefania, Fremont, Daved H, Jiang, Xiaoping, Lebratti, Tania J, Richner, Justin M, Scott, Jason M, Shin, Haina, Zhao, Haiyan   +8 more
core   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Implication of sexual transmission of Zika on dengue and Zika outbreaks

Mathematical Biosciences and Engineering, 2019
Dengue and Zika viruses belong to the same Flavivirus family and usually cocirculate within the same area. Both the viruses can be transmitted by a common mosquito species Aedes aegypti.
Biao Tang , Weike Zhou, Yanni Xiao, Jianhong Wu   +3 more
doaj   +1 more source

The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection

Viruses, 2023
Ebola virus (EBOV) causes Ebola virus disease (EVD), which is characterized by hemorrhagic fever with high mortality rates in humans. EBOV sexual transmission has been a concern since the 2014–2016 outbreak in Africa, as persistent infection in the ...
Olivier Escaffre, Terry L. Juelich, Jennifer K. Smith, Lihong Zhang, Nigel Bourne, Alexander N. Freiberg   +5 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source