Results 51 to 60 of about 487,907 (301)

Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model

Cell Reports, 2017
Circulation of Zika virus (ZIKV) was first identified in the Western hemisphere in late 2014. Primarily transmitted through mosquito bite, ZIKV can also be transmitted through sex and from mother to fetus, and maternal ZIKV infection has been associated ...
Nisha K. Duggal, Jana M. Ritter, Samuel E. Pestorius, Sherif R. Zaki, Brent S. Davis, Gwong-Jen J. Chang, Richard A. Bowen, Aaron C. Brault   +7 more
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Zika Virus in the Male Reproductive Tract

Viruses, 2018
Arthropod-borne viruses (arboviruses) are resurging across the globe. Zika virus (ZIKV) has caused significant concern in recent years because it can lead to congenital malformations in babies and Guillain-Barré syndrome in adults.
Liesel Stassen, Charles W. Armitage, David J. van der Heide, Kenneth W. Beagley, Francesca D. Frentiu   +4 more
doaj   +1 more source

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. [PDF]

, 2008
BACKGROUND: Artemisinin combination therapies (ACT), which are increasingly being introduced for treatment of Plasmodium falciparum malaria, are more effective against sexual stage parasites (gametocytes) than previous first-line antimalarials and ...
Bousema, Teun, Drakeley, Chris J, Ghani, Azra C, Okell, Lucy C, Sutherland, Colin J   +4 more
core   +3 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Non-Feeding Transmission Modes of the Tomato Yellow Leaf Curl Virus by the Whitefly Bemisia tabaci Do Not Contribute to Reoccurring Leaf Curl Outbreaks in Tomato

Insects
Tomato yellow leaf curl virus (TYLCV) causes significant yield loss in tomato production in the southeastern United States and elsewhere. TYLCV is transmitted by the whitefly Bemisia tabaci cryptic species in a persistent, circulative, and non ...
Wendy G. Marchant, Judith K. Brown, Saurabh Gautam, Saptarshi Ghosh, Alvin M. Simmons, Rajagopalbabu Srinivasan   +5 more
doaj   +1 more source

The Dual Role of the Immune Response in Reproductive Organs During Zika Virus Infection

Frontiers in Immunology, 2019
Zika virus is a mosquito-borne viral disease that emerged as a significant health problem in the Americas after an epidemic in 2015. Especially concerning are cases where Zika is linked to the development of brain abnormalities in newborns.
Haruki Arévalo Romero, Tania A. Vargas Pavía, Manuel A. Velázquez Cervantes, Arturo Flores Pliego, Addy C. Helguera Repetto, Moises León Juárez   +5 more
doaj   +1 more source

What use are male hosts? The dynamics of maternally inherited bacteria showing sexual transmission or male killing [PDF]

, 2009
Closely related pathogens and parasites often have distinctly different strategies for transmission. In some cases, presence of one potential mode of transmission reduces the rate of or forbids another. In these cases, one can ask what the conditions are
Engelstaedter, Jan, Hurst, Gregory D. D.
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Spatial variation in the incidence of a sexually transmitted parasite of the ladybird beetle Adalia bipunctata (Coleoptera: Coccinellidae)

European Journal of Entomology, 2006
Whilst sexually transmitted pathogens and parasites are common on insects and other animals, the factors affecting their incidence are currently uncertain.
K. WEBBERLEY, Matthew C. TINSLEY, John J. SLOGGETT, Michael E.N. MAJERUS, Gregory D.D. HURST   +4 more
doaj   +1 more source