Results 61 to 70 of about 11,531 (311)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Ruling Sexualities: Sexuality, Gender, and the Crown: An Introduction

open access: yesRoyal Studies Journal, 2019
This article serves as an introduction to the Royal Studies Journal “Ruling Sexualities” Special Issue. It begins with a brief explanation for the creation of this special issue and a discussion of the diverse approaches that each article takes towards ...
Katia Wright   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

A Tale of Two South Africans – A review

open access: yesSouth African Journal of Science, 2022
Rebecca Hodes
doaj   +1 more source

Living “Gender Empowerment” in Disaster and Diverse Space: Youth, Sexualities, Social Change, and Post-Hurricane Katrina Generations

open access: yesYouth
This article explores the notion of “gender empowerment” in relation to feminist claims around collectivity and the real lives of young women and non-binary people who grew up in post-Katrina New Orleans.
Lisa Rose-Anne Overton   +1 more
doaj   +1 more source

“Do anel à aliança”: Sentido dos iguais e emancipação pessoal na psicologia das sexualidades

open access: yesRevista Crítica de Ciências Sociais, 2006
Systematizing some of the processes that underlie the psychological development of (sexual) identity, this paper proposes a Critical Psychosocial Analysis of contemporary sexualities.
Nuno Santos Carneiro, Isabel Menezes
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen   +11 more
wiley   +1 more source

Dilemas Éticos e Metodológicos na Investigação das Sexualidades do Adulto Idoso: o Caso de uma Tese de Mestrado em Educação para a Saúde

open access: yesSisyphus, 2018
Resumo Em Portugal, apesar da ciência e meios de comunicação precipitarem a visibilidade das sexualidades do adulto idoso, forças históricas e sociais continuam a perpetuar a sua omissão.
Ana Ferreira Silva   +1 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

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