Results 51 to 60 of about 640,334 (365)
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
Comprehensive Sexuality Education [PDF]
Healthy Teen Network recommends and encourages the teaching of developmentally and age-appropriate comprehensive sexuality education, as it holds the greatest hope for reducing the risk of sexually transmitted infections (STIs) and unintended pregnancy ...
core
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Sexual Interactions and Sexual Infidelity [PDF]
AbstractThis paper establishes what constitutes a sexual interaction between two or more people. It does this by first defining a sexual activity as one in which the agent intends to satisfy a sexual desire (i.e. a desire for sexual pleasure). To understand what it means to engage in a sexual activity with another person, it draws from Bratman’s ...
openaire +4 more sources
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Queer Farmers: Sexuality and the Transition to Sustainable Agriculture [PDF]
Intimate relationships are foundational to farm viability. Such relationships affect how farmers share tasks, earn income, and access land, yet the role of sexuality and heteronormativity in agriculture remains understudied.
Leslie, Isaac
core +2 more sources
Evaluation of a school based comprehensive sexuality education program among very young adolescents in rural Uganda [PDF]
Background: Limited research has been conducted on the effectiveness of sexuality education for very young adolescents (VYAs) ages 10-14 years in Sub-Saharan Africa.
Bruce, Katherine+9 more
core +2 more sources
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Lesbian and bisexual women's experiences of sexuality-based discrimination and their appearance concerns [PDF]
Lesbian and bisexual women frequently experience sexuality-based discrimination, which is often based on others' judgements about their appearance. This short article aims to explore whether there is a relationship between lesbian and bisexual women's ...
Bower J.+29 more
core +1 more source