Results 61 to 70 of about 236,714 (368)
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
Background Sexual health is generally considered an integral part of medical and allied healthcare professional training. However, many medical schools do not offer this as a mandatory curriculum, or minimize it.
Michael W. Ross+3 more
doaj +1 more source
Challenging and Reinforcing the Ability/Disability System through Advocacy for Disabled Dogs
This paper illuminates how volunteers and animal rescuers who assist dogs from a high-intake public shelter in the Los Angeles metropolitan area simultaneously resist the devaluation of the lives of disabled dogs while sensationalizing and fetishizing ...
Katja M. Guenther
doaj +1 more source
Sex-specific recombination rates and allele frequencies affect the invasion of sexually antagonistic variation on autosomes [PDF]
The introduction and persistence of novel sexually antagonistic alleles can depend upon factors that differ between males and females. Understanding the conditions for invasion in a two-locus model can elucidate these processes. For instance, selection can act differently upon the sexes, or sex-linkage can facilitate the invasion of genetic variation ...
arxiv +1 more source
Sexual Interactions and Sexual Infidelity [PDF]
AbstractThis paper establishes what constitutes a sexual interaction between two or more people. It does this by first defining a sexual activity as one in which the agent intends to satisfy a sexual desire (i.e. a desire for sexual pleasure). To understand what it means to engage in a sexual activity with another person, it draws from Bratman’s ...
openaire +4 more sources
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
wiley +1 more source
Evaluating distributional regression strategies for modelling self-reported sexual age-mixing [PDF]
The age dynamics of sexual partnership formation determine patterns of sexually transmitted disease transmission and have long been a focus of researchers studying human immunodeficiency virus. Data on self-reported sexual partner age distributions are available from a variety of sources.
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
Background Sexual health is recognized as a fundamental component of well-being, with implications for individuals, communities, and healthcare practices.
Evelien Bogaert, Rick Roels
doaj +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source