Results 61 to 70 of about 670,551 (364)

Comprehensive Sexuality Education [PDF]

open access: yes, 2008
Healthy Teen Network recommends and encourages the teaching of developmentally and age-appropriate comprehensive sexuality education, as it holds the greatest hope for reducing the risk of sexually transmitted infections (STIs) and unintended pregnancy ...

core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Sexual Health and Sexual Behavior [PDF]

open access: yes, 2020
Both academic and lay definitions of sex vary. However, definitions generally gravitate around reproduction and the experience of pleasure. Some theoretical approaches, such as psychoanalysis and evolutionary psychology, have positioned sexuality at the center of psychological phenomena. Much research has also linked sex to health and disease.
openaire   +1 more source

Queer Farmers: Sexuality and the Transition to Sustainable Agriculture [PDF]

open access: yes, 2016
Intimate relationships are foundational to farm viability. Such relationships affect how farmers share tasks, earn income, and access land, yet the role of sexuality and heteronormativity in agriculture remains understudied.
Leslie, Isaac
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Criminología sexual*

open access: yesREVISTA IUS, 2016
La tasa de delitos sexuales sigue creciendo, afectando principalmente a mujeres jóvenes y a la niñez, sin que exista una respuesta institucional adecuada para su prevención, atención y erradicación. Conductas delictivas con fuerte rechazo social pero difícil comprensión científica, al menos desde un enfoque interdisciplinario eficaz.
Erick Gómez Tagle López   +1 more
openaire   +3 more sources

Sexuality and Reproduction [PDF]

open access: yes, 2004
No abstract ...
Church, Sarah, Earle, Sarah
core  

Pop stars and idolatry: an investigation of the worship of popular music icons, and the music and cult of Prince. [PDF]

open access: yes, 2010
Prince is an artist who integrates elements from the sacred into his work. He uses popular iconography to present himself as an icon of consumer culture, as a deified ‘rock god’ worshipped by his fans, and as a preacher leading his audience like a ...
Baty S. Paige   +23 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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