Results 71 to 80 of about 236,714 (368)

“And the House Burned Down”: HIV, Intimacy, and Memory in Danez Smith’s Poetry

open access: yesOpen Cultural Studies, 2023
Danez Smith’s [insert] boy (2014) not only bears witness to the intricacy of the intersection between queerness and Blackness in the United States of the twenty-first century, but also illustrates an overcoming of multiple forms of oppression through ...
Juncosa Toni R.
doaj   +1 more source

Making Bedlam: Toward a Trauma-Informed Mad Feminist Literary Theory and Praxis

open access: yesHumanities, 2023
Building on what Margaret Price describes as the “long history of positive and person-centered discourses” of the term Mad, this article seeks to offer a (re)tooling and (re)theorization of the not-so-antiquated concept of “bedlam” as part of a Mad ...
Jessica Lowell Mason
doaj   +1 more source

The...Tinderverse?: Opportunities and Challenges for User Safety in Extended Reality (XR) Dating Apps [PDF]

open access: yesarXiv, 2022
Dating apps such as Tinder have announced plans for a dating metaverse: the incorporation of XR technologies into the online dating process to augment interactions between potential sexual partners across virtual and physical worlds. While the dating metaverse is still in conceptual stages we can forecast significant harms that it may expose daters to ...
arxiv  

Mathematical toy model inspired by the problem of the adaptive origins of the sexual orientation continuum [PDF]

open access: yesRoyal Society Open Science 3: 160403 (2016), 2015
Same-sex sexual behavior is ubiquitous in the animal kingdom, but its adaptive origins remain a prominent puzzle. Here I suggest the possibility that same-sex sexual behavior arises as a consequence of the competition between an evolutionary drive for a wide diversity in traits, which improves the adaptability of a species, and a drive for sexual ...
arxiv   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Synergy from reproductive division of labor and genetic complexity drive the evolution of sex [PDF]

open access: yesJ Biol Phys (2018). https://doi.org/10.1007/s10867-018-9485-8, 2017
Computer experiments that mirror the evolutionary dynamics of sexual and asexual organisms as they occur in nature, tested features proposed to explain the evolution of sexual recombination. Results show that this evolution is better described as a network of interactions between possible sexual forms, including diploidy, thelytoky, facultative sex ...
arxiv   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Between Needs and Taboos: Sexuality and Reproductive Health Education for High School Students

open access: yesMakara Journal of Health Research, 2013
This paper examines reproductive health and sexuality education for adolescents that has been conducted by government and non-government at the high school level.
Diana Teresa Pakasi, Reni Kartikawati
doaj   +1 more source

Mathematical models of SIR disease spread with combined non-sexual and sexual transmission routes [PDF]

open access: yesarXiv, 2016
The emergence of diseases such as Zika and Ebola has highlighted the need to understand the role of sexual transmission in the spread of diseases with a primarily non-sexual transmission route. In this paper we develop a number of low-dimensional models which are appropriate for a range of assumptions for how a disease will spread if it has sexual ...
arxiv  

SEXUALITY and SEXUAL EDUCATION

open access: yesTurkish Journal of Family Medicine & Primary Care, 2015
We are such kind of a society that considers sexuality still as disgraceful,forbidden and sinful which is in fact defined as an important component of an individual's personality and self distinctiveness. Just for this reason, even its history has initiated with the history of human beings, sexuality is still a subject which is denied and avoided to ...
Aydan Aksöyek, Taner Canatar
openaire   +2 more sources

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