Results 171 to 180 of about 386,739 (299)

Distinct Biotypes of Visual Perception in Major Depressive Disorder

Advanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai, Xi‐Wen Hu, Yuyang Li, Zheng Lin, Yongjie Li, Yong‐Chun Cai, Tao Xu, Ke Jia, Jin‐Fang Han, Zhong‐Lin Tan, Dezhong Yao, Xue Mei Song, Sugai Liang, Georg Northoff   +13 more
wiley   +1 more source

Implementation of a Whole-School Relationship and Sexuality Education Project in Western Australian Schools: Evaluation Data From a Multiple, Embedded Case Study. [PDF]

Health Promot J Austr
Burns S, Glasgow-Collins R, Saltis H, Hendriks J.   +3 more
europepmc   +1 more source

Educating ideal neoliberal citizens: discourses of agency and responsibility in comprehensive sexuality education. [PDF]

Sex Reprod Health Matters, 2023
Lewinger S.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Building multi-sectoral alliances to co-design and pilot a gender-transformative comprehensive sexuality education intervention for adolescents: the case of Si Yo Fuera Juan in Uruguay. [PDF]

Reprod Health
López Gómez A, Lohan M, Costa M, Ramos MS, De Rosa L, Rossi S, López P.   +6 more
europepmc   +1 more source

Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

Advanced Science, EarlyView.
Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li, Yue Wang, Xiufang Liang, Mengze Xu, David T. Leong, Pu Chun Ke   +5 more
wiley   +1 more source

A farewell to abstinence and fidelity?

The Lancet Global Health, 2016
Kent Buse, Mikaela Hildebrand, Sarah Hawkes   +2 more
doaj   +1 more source

'One Size Does Not Fit All'. The Voices of Professionals Regarding the Delivery of Relationships and Sexuality Education to Children and Young People With Intellectual Disability: Findings From a UK-Wide Qualitative Study. [PDF]

J Appl Res Intellect Disabil
Brown M, Linden M, Marsh L, Truesdale M, Sheerin F, McCormick F.   +5 more
europepmc   +1 more source

A Meta-Analysis of the Effects of Comprehensive Sexuality Education Programs on Children and Adolescents. [PDF]

Healthcare (Basel), 2023
Kim EJ, Park B, Kim SK, Park MJ, Lee JY, Jo AR, Kim MJ, Shin HN.   +7 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source