Results 51 to 60 of about 218,257 (329)

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Characteristics of HIV/AIDS cases identified in medical institutions versus voluntary counseling and testing clinics in Liaoning province, 2018–2024

Zhongguo gonggong weisheng
Objective To compare the characteristics of HIV/AIDS cases detected through medical institutions and voluntary counseling and testing (VCT) clinics in Liaoning province, China, from 2018 to 2024.
Lixiang SUN, Dan ZHOU, Shan PAN, Haiyang YU, Ya′nan TAO   +4 more
doaj   +1 more source

Core groups and the transmission of HIV: Learning from male sex workers [PDF]

, 2005
A growing and substantial body of research suggests that female sex workers play a disproportionately large role in the transmission of HIV in many parts of the world, and they are often referred to as core groups by epidemiologists, mathematical ...
Parker, M
core   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

A rapid isothermal CRISPR-Cas13a diagnostic test for genital herpes simplex virus infection

iScience
Summary: Prompt diagnosis is essential for managing herpes simplex virus types 1 and 2 (HSV-1/2). Existing diagnostic methods are not widely available that required expensive or additional equipment for conducting examinations and result readouts, which ...
Xiaona Yin, Hao Luo, Han Zhou, Ziyan Zhang, Yinyuan Lan, Zhanqin Feng, Wentao Chen, Heping Zheng   +7 more
doaj   +1 more source

Primary care of patients with sexually transmitted diseases or genitourinary symptoms in Hong Kong [PDF]

, 2005
Objectives. To determine the adequacy of care received from general practitioners by patients with sexually transmitted diseases or genitourinary symptoms. Design. Prospective study. Setting. Hong Kong. Participants. Diagnoses and drug data obtained from
Chan, C, Dickinson, JA, Wong, WCW
core  

Conocimientos de adolescentes sobre Enfermedades Sexualmente Transmisibles: subsidios para la prevención [PDF]

, 2009
Objective: To identify teenager's knowledge of transmission and prevention of sexually transmitted diseases (STD). Methods: A sample of children and teenagers aged between 10 and 19 years participated in the study.
Brêtas, José Roberto da Silva, Jardim, Dulcilene Pereira, Muroya, Renata de Lima, Ohara, Conceicao Vieira da Silva   +3 more
core   +3 more sources

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source

Poor Women with Sexually Transmitted Infections: Providers’ Perspectives on Diagnoses [PDF]

, 2011
This article presents results from a study of health care providers, mainly nurses and nurse practitioners, who routinely diagnose sexually transmitted diseases (STDs) in rural low-income populations in West Virginia (WV).
Cox, Genevieve R.
core   +1 more source

Obtaining self-samples to diagnose curable sexually transmitted infections: a systematic review of patients' experiences [PDF]

, 2015
BACKGROUND: Routine screening is key to sexually transmitted infection (STI) prevention and control. Previous studies suggest that clinic-based screening programmes capture only a small proportion of people with STIs.
Lau, Jason, Llewellyn, Carrie, Mahmud, Mohammad, Paudyal, Priyamvada, Smith, Helen   +4 more
core   +4 more sources