Results 61 to 70 of about 2,556,615 (303)

A rapid isothermal CRISPR-Cas13a diagnostic test for genital herpes simplex virus infection

iScience
Summary: Prompt diagnosis is essential for managing herpes simplex virus types 1 and 2 (HSV-1/2). Existing diagnostic methods are not widely available that required expensive or additional equipment for conducting examinations and result readouts, which ...
Xiaona Yin, Hao Luo, Han Zhou, Ziyan Zhang, Yinyuan Lan, Zhanqin Feng, Wentao Chen, Heping Zheng   +7 more
doaj   +1 more source

Conquering sexually transmitted diseases [PDF]

Nature Reviews Immunology, 2008
Sexually transmitted diseases (STDs) are a major public-health problem and also a significant financial burden on the economy. Past and ongoing attempts to create vaccines against sexually transmitted pathogens have met with varying success. This article highlights some of the public-health and social problems that are associated with STDs and the ...
Michael N, Starnbach, Nadia R, Roan
openaire   +2 more sources

Risk pathways for gonorrhea acquisition in sex workers: can we distinguish confounding from an exposure effect using a priori hypotheses? [PDF]

, 2014
The population distribution of sexually transmitted infections (STIs) varies broadly across settings. Although there have been many studies aiming to define subgroups at risk of infection that should be a target for prevention interventions by ...
Garnett, Geoffrey P, Gomez, GB, Ward, H, Gomez, Gabriela B, Ward, Helen, Gomez, Gabriela B., Garnett, GP, Garnett, Geoffrey P.   +7 more
core   +1 more source

Place‐based risk: Examining relationships between adolescent perceptions of community risk factors and adolescent substance use across geographic contexts

American Journal of Community Psychology, EarlyView.
Abstract Mixed evidence for the influence of structural and social factors on adolescent substance use behaviors exists across the rural–urban continuum. Therefore, this study explores how adolescent perceptions of structural and social community risk factors are associated with lifetime and past 30‐day use of alcohol, marijuana, cigarettes, and ...
Melissa Pearman Fenton, Sarah D. Lynne, Josie L. Bryan, Catherine Woodstock Striley, Larry F. Forthun   +4 more
wiley   +1 more source

Functionally-informed fine-mapping identifies genetic variants linking increased CHD1L expression and HIV restriction in monocytes

Scientific Reports
Human Immunodeficiency Virus Type 1 (HIV) set-point viral load is a strong predictor of disease progression and transmission risk. A recent genome-wide association study in individuals of African ancestries identified a region on chromosome 1 ...
Riley H. Tough, Paul J. McLaren, The International Collaboration for the Genomics of HIV   +2 more
doaj   +1 more source

Rapid, low-cost, and portable molecular detection of HIV-1 subtype B and HCV 1a directly from blood

Microbiology Spectrum
Accessible molecular diagnostics for human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) remain constrained by the cost and infrastructure requirements of existing molecular point-of-care platforms.
David M. Tang, Karen Michalak, Kelvin Nguyen, Philip Lacap, John Kim, Paul J. McLaren   +5 more
doaj   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source

1989 Sexually Transmitted Diseases Treatment Guidelines [PDF]

These guidelines for the treatment of patients with sexually transmitted diseases (STD) were established after consultation with a group of outside experts and staff of CDC.

core  

Reproductive health for refugees by refugees in Guinea II: sexually transmitted infections. [PDF]

, 2008
BACKGROUND: Providing reproductive and sexual health services is an important and challenging aspect of caring for displaced populations, and preventive and curative sexual health services may play a role in reducing HIV transmission in complex ...
Akaco Ekirapa, Souare, Yaya, Chen Mark I, Natasha Howard, Ekirapa, Akaco, Ekirapa Akaco, Mark I Chen, von Roenne Franz, von Roenne, Franz, von Roenne Anna, Chen, Mark I, von Roenne, Anna, Howard, Natasha, Howard Natasha, Franz von Roenne, Borchert Matthias, Anna von Roenne, Souare Yaya, Matthias Borchert, Yaya Souare, Borchert, Matthias   +20 more
core   +1 more source