Results 61 to 70 of about 218,257 (329)

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Functionally-informed fine-mapping identifies genetic variants linking increased CHD1L expression and HIV restriction in monocytes

Scientific Reports
Human Immunodeficiency Virus Type 1 (HIV) set-point viral load is a strong predictor of disease progression and transmission risk. A recent genome-wide association study in individuals of African ancestries identified a region on chromosome 1 ...
Riley H. Tough, Paul J. McLaren, The International Collaboration for the Genomics of HIV   +2 more
doaj   +1 more source

Victory Congress in Vitória, Brazil

DST, 2022
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NEIDE TOSATO BOLDRINI, EDILBERT PELLEGRINI, JOSÉ ELEUTÉRIO JR.   +2 more
doaj  

Knowledge, Prevalence and Factors Associated with Sexually Transmitted Diseases among Female Students of a Federal University in Southern Nigeria [PDF]

, 2022
Chimezie Igwegbe Nzoputam, Vincent Yakubu Adam, Ogochukwu Janet Nzoputam   +2 more
openalex   +1 more source

Gambaran Pengetahuan Remaja Tentang Penyakit Menular Seksual (Hiv/aids) Di Desa Alasgung Kec Sugihwaras [PDF]

, 2015
Adolescent is a period of transition from childhood to adulthood. The phenomenon that occurred in the village of Alasgung still many teenagers who are not informed about HIV AIDS, coupled with the development of highly advanced technology where they can ...
IRWANTO, I. (IRWANTO), PATONAH, S. (SITI), S, A. S. (ATIK)   +2 more
core  

Sexually Transmitted Infections and Sexual Behaviour Among Commercial Sex Workers in a Rural District of Malawi. [PDF]

, 2003
In Thyolo District, Malawi, a study was conducted among commercial sex workers (CSWs) attending mobile clinics in order to; determine the prevalence and pattern of sexually transmitted infections (STIs), describe sexual behaviour among those who have an ...
Arendt, V, Chantulo, A, Harries, A D, Nkhoma, W, Spielmann M P, Zachariah, R   +5 more
core   +2 more sources

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

ABC of sexually transmitted infections - Main presentations of sexually transmitted infections in men [PDF]

, 2004
This article is adapted from the fifth edition of the ABC ofSexually Transmitted Diseases, which is published by BMJBooks (www.bmjbooks.com).Some sexually transmitted infections, such as gonorrhoea and chlamydial infection, have different presentations ...
Richens, J
core  

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

Atypical Blistering Manifestation of Secondary Syphilis: Case Report and Review of Reported Cases

Infectious Disease Reports
Background/Objectives: Secondary syphilis typically presents with a non-pruritic maculopapular rash. However, vesicular and bullous manifestations are exceedingly rare in adults and may mimic autoimmune blistering diseases.
Agnieszka Markiewicz, Aleksandra Skórka, Agnieszka Owczarczyk-Saczonek   +2 more
doaj   +1 more source