Results 191 to 200 of about 82,571 (257)

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

open access: yesInterdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen   +6 more
wiley   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

open access: yesInterdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Predicting Major Depression Among Diverse Online Gamers: The Role of Internet Addiction and Spirituality

open access: yesJournal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study analyzed whether religious or spiritual affiliation and therapy enrollment protect against symptoms meeting Major Depressive Disorder criteria beyond demographic, Internet addiction, and described therapy enrollment. Findings illustrated one risk factor and one protective factor associated with experiencing symptoms that meet Major ...
Lindsay A. Lundeen, John R. McCall
wiley   +1 more source

Effective Altruism and Care Ethics

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Effective altruism (EA) has received some of its most vocal criticisms from supporters of care ethics. In this article I take a comparative approach to determine whether a compelling critique of EA can emerge from care ethics at the ethical level, and more generally how much common ground can be found between the two.
Antonin Broi
wiley   +1 more source

Mother Earth: Climate Justice, Infant Feeding Decisions, and Intimacy

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Human infants require milk. This can be parental milk provided directly from the parent's body (known as breastfeeding, chestfeeding, or nursing), expressed human milk, or infant formula milk. This article contributes to the literature on the ethics of infant feeding in two ways. First, it brings recent research on the climate impact of infant
Fiona Woollard
wiley   +1 more source

Psychometric Analysis of Scores on the GAD‐7 With University Students

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT This study explored the psychometric characteristics of the Generalized Anxiety Disorder seven‐item screener (GAD‐7) scores. The 568 US university student participant responses yielded a unidimensional factor structure with mostly excellent fit statistics.
Elizabeth L. Sweeting   +5 more
wiley   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Low‐Level Human Epididymis Protein 4 in Seminal Plasma Is an Independent Risk Factor for Poor Semen Liquefaction: A Case Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Our work identifies a novel and significant association between low seminal levels of Human Epididymis Protein 4 (HE4) and the clinical condition of poor semen liquefaction, a common cause of male infertility. The findings are statistically robust, clinically relevant, and provide a foundational basis for future research into the mechanism by which HE4
Feifei Wang   +5 more
wiley   +1 more source

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