Results 81 to 90 of about 218,257 (329)
Advanced Science, EarlyView.Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
Predictors of incident herpes simplex virus type 2 infections in young women at risk for unintended pregnancy in San Francisco. [PDF]
, 2007 BackgroundYoung women receiving family planning services are at risk for both unintended pregnancy and herpes simplex virus type 2 (HSV-2) infection.MethodsWe performed a secondary analysis using data from a previously published randomized controlled ...
Ahrens, Katherine +7 more
core +3 more sources
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Sexually Transmitted Parasitic Diseases [PDF]
Clinics in Colon and Rectal Surgery, 2004 An increasing number of diseases are recognized as being sexually transmitted. The majority of these are bacterial or viral in nature; however, several protozoan and nematode infections can also be transmitted by sexual activity. For most of these diseases, the primary mode of transmission is nonsexual in nature, but sexual activity that results in ...
openaire +2 more sources
A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation
Advanced Science, EarlyView.We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong +4 more
wiley +1 more source
Medicina, 2020 Background and objectives: The shared pathogenesis of psoriasis and atherosclerosis may be determined by assaying the levels of endothelial activation molecules.
Natalia Zdanowska +7 more
doaj +1 more source
The operation of a venereology clinic in the West End of London [PDF]
, 1976 A period of employment at James Pringle House provided the opportunity of observing how the growing problem of sexually transmitted diseases is being dealt with in London.
Vella Briffa, D.
core
AIDS Surveillance in Africa [PDF]
, 1991 Surveillance of the AIDS pandemic in Africa has always posed formidable problems for epidemiologists. Diagnostic accuracy-according to the case definitions for AIDS used in industrialised countries-is impossible to achieve in all but a few places with ...
BIGGAR, R.J., KILLEWO, J., NICOLL, A.
core +1 more source
Laparoscopic Colorectal Surgery in the Era of Robotics: Evolution, Eclipse, or Equilibrium?
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Minimally invasive colorectal surgery has undergone a remarkable transformation over the past three decades. Laparoscopy, once viewed with skepticism, is now firmly established as a standard approach, supported by robust randomized trials demonstrating oncologic safety and improved recovery compared to open surgery.
Amanjeet Singh +3 more
wiley +1 more source