Results 131 to 140 of about 90,175 (266)

From Disability to Diagnosis: Baseline Findings from the Calgary Functional Movement Disorder Registry

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Functional movement disorder (FMD), a subtype of functional neurological disorder, is a complex neuropsychiatric syndrome characterized by inconsistent and incongruent motor symptoms. Despite its relatively high prevalence, FMD remains associated with delayed diagnosis, significant disability, and limited evidence to guide ...
Andrea Soumbasis   +6 more
wiley   +1 more source

Continuous Subcutaneous Foslevodopa/Foscarbidopa in Advanced Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Continuous subcutaneous foslevodopa/foscarbidopa (LDp/CDp) provides 24‐h delivery of levodopa‐carbidopa prodrugs for advanced Parkinson's disease. Real‐world 1‐year European data remain limited. Objectives To characterize 1‐year changes in motor, non‐motor, autonomic, quality‐of‐life and sleep outcomes, and in concomitant therapy ...
Mario Hero   +5 more
wiley   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

open access: yesMed Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen   +10 more
wiley   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

open access: yesMovement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin   +10 more
wiley   +1 more source

Correlates of Sexually Transmitted Infection (STI) Positivity and Implementation of Point-of-Care STI Testing at a Mobile Clinic for Women Who Inject Drugs in Seattle, WA. [PDF]

open access: yesSex Transm Dis
Fessler AG   +10 more
europepmc   +1 more source

Chronic Ulcer on the Vulva

open access: yes
JEADV Clinical Practice, EarlyView.
Farhanaz Panjshiri   +2 more
wiley   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood   +7 more
wiley   +1 more source

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