Results 81 to 90 of about 411,551 (395)

Interplay among Vaginal Microbiome, Immune Response and Sexually Transmitted Viral Infections

open access: yesInternational Journal of Molecular Sciences, 2019
The vaginal ecosystem is important for women’s health and for a successful reproductive life, and an optimal host-microbial interaction is required for the maintenance of eubiosis.
M. Torcia
semanticscholar   +1 more source

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

open access: yesAdvanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo   +14 more
wiley   +1 more source

Should Mycoplasma penetrans be considered a pathogen in anal specimens from men who have sex with men?

open access: yesInternational Journal of Infectious Diseases
Objectives: This study was performed to assess the prevalence of Mycoplasma penetrans in anal samples collected from men who have sex with men (MSM) undergoing screening for Chlamydia trachomatis and Neisseria gonorrhoeae and to identify factors ...
Audrey Tokpassi   +4 more
doaj   +1 more source

Study protocol for data to suppression (D2S): a cluster-randomised, stepped-wedge effectiveness trial of a reporting and capacity-building intervention to improve HIV viral suppression in housing and behavioural health programmes in New York City

open access: yesBMJ Open, 2023
Introduction With progress in the ‘diagnose’, ‘link’ and ‘retain’ stages of the HIV care continuum, viral suppression (VS) gains increasingly hinge on antiretroviral adherence among people with HIV (PWH) retained in care.
Meghan Peterson   +9 more
doaj   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

What do primary care staff know and do about blood borne virus testing and care for migrant patients? A national survey

open access: yesBMC Public Health, 2021
Background UK migrants born in intermediate to high prevalence areas for blood borne viruses (BBV) including hepatitis B, hepatitis C and HIV are at increased risk of these infections.
Rachel Roche   +10 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

GAMBARAN PENGETAHUAN DAN SIKAP REMAJA MAN MODEL BANDA ACEH TERHADAP INFEKSI MENULAR SEKSUAL TAHUN 2012 [PDF]

open access: yes, 2016
Until recently sexually transmitted infections is still a problem in the fieldof health, social and economic development in various countries. In somecountries stated that the provision of an intensive counseling program wouldreduce the prevalence of ...
FAUZAN
core  

Sexually transmitted infections and HIV in the era of antiretroviral treatment and prevention: the biologic basis for epidemiologic synergy

open access: yesJournal of the International AIDS Society, 2019
HIV is a unique sexually transmitted infection (STI) that is greatly affected by other concomitant “classical” bacterial and viral STIs that cause genital ulcers and/or mucosal inflammation. STIs also serve as a marker for risky sexual behaviours.
M. Cohen   +2 more
semanticscholar   +1 more source

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