Results 61 to 70 of about 282,765 (338)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Psychometric Evaluation and Establishing Norms of Croatian SF-36 Health Survey: Framework for Subjective Health Research [PDF]

, 2006
Aim: To provide population norms and evaluate metric characteristics of the Croatian version of SF-36 Health Survey, an internationally used instrument for assessing subjective health. Method: The questionnaire was administered to a representative sample
Darja Maslić Seršić, Gorka Vuletić
core   +2 more sources

Sample size and power estimation for studies with health related quality of life outcomes: a comparison of four methods using the SF-36 [PDF]

, 2004
We describe and compare four different methods for estimating sample size and power, when the primary outcome of the study is a Health Related Quality of Life (HRQoL) measure. These methods are: 1.
Walters, Stephen J.
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Validation of the SF-36 in patients with endometriosis. [PDF]

, 2013
OBJECTIVES: Endometriosis presents with significant pain as the most common symptom. Generic health measures can allow comparisons across diseases or populations.
A Bergqvist, A Marques, Antje Colligs, B Eskenazi, C Acquadro, CH Bodner, Christian Seitz, Christoph Gerlinger, DC Turk, DE Stull, Donald E. Stull, E Beivik, E Gerety, FW Ling, G Dubernard, G Jones, G Jones, G Jones, GL Jones, HH Colwell, J Beals, J Cohen, JA Abbott, JD Miller, JE Carter, JE Ware, JE Ware, JE Ware, JT Farrar, K Plumb, KA Burry, KJ Yost, KO Biberoglu, L Busija, L Hummelshoj, Mireia Raluy, MK Rowe, ML Ballweg, MP Vessey, MW Browne, N Sinaii, Noemi Kreif, O Chassany, P Banks, P Barton-Smith, P Butterworth, P Vigano, PJ Reed, PR Koninckx, R Garry, R Shikiar, Radek Wasiak, RB Kline, S Ferrero, S Kennedy, S Ozkan, SD Lyons, SD Mathias, T Strowitzki, T Strowitzki, TA Mahmood, W Guy, WD Schlaff, X Gao, Y Ozawa   +64 more
core   +3 more sources

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

A cross-sectional study of QOL of diabetic patients at tertiary care hospitals in Delhi

Indian Journal of Community Medicine, 2009
Background: According to WHO estimates India will be the global capital of diabetes by 2025, accounting for 57.2 million diabetics. Worsening the situation is the fact that diabetes affects the economically productive age-group (45-65 years) in ...
Gautam Yogesh, Sharma A, Agarwal A, Bhatnagar M, Trehan Roochika   +4 more
doaj  

The Health Impact of Symptomatic Adult Spinal Deformity: Comparison of Deformity Types to United States Population Norms and Chronic Diseases. [PDF]

, 2016
Study designA retrospective analysis of a prospective, multicenter database.ObjectiveThe aim of this study was to evaluate the health impact of symptomatic adult spinal deformity (SASD) by comparing Standard Form Version 2 (SF-36) scores for SASD with ...
Akbarnia, Behrooz, Ames, Christopher, Bess, Shay, Burton, Douglas, Fu, Kai-Ming, Hart, Robert, Hostin, Richard, International Spine Study Group, Jo, Han, Kebaish, Khaled, Kelly, Michael, Klineberg, Eric, Lafage, Virgine, Line, Breton, McCarthy, Ian, Mummaneni, Praveen, Mundis, Gregory, Schwab, Frank, Shaffrey, Christopher, Smith, Justin S   +19 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source