Amaç: Lomber disk hernisi (LDH) tanısı koyulan ve mikrodiskektomi cerrahisi geçiren bireylerde kinezyofobi, günlük yaşam aktiviteleri ve uyku kalitesinin değişimini araştırmaktır. Materyal&Method: LDH cerrahisi endikasyonu olup, cerrahi olan 30 hasta
Nurgül Dürüstkan Elbaşı +2 more
doaj +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Psychometric Evaluation and Establishing Norms of Croatian SF-36 Health Survey: Framework for Subjective Health Research [PDF]
Aim: To provide population norms and evaluate metric characteristics of the Croatian version of SF-36 Health Survey, an internationally used instrument for assessing subjective health. Method: The questionnaire was administered to a representative sample
Darja Maslić Seršić, Gorka Vuletić
core +2 more sources
Atividade física e qualidade de vida associada à saúde em idosos participantes e não participantes em programas regulares de atividade física [PDF]
This study goals were: 1) compare the health-related quality of life between elderly who attend formal exercise activities and those who did not and, 2) determine the predictive factors that allow such participation.The total sample was comprised of 88 ...
Joana Carvalho +3 more
core +2 more sources
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Sample size and power estimation for studies with health related quality of life outcomes: a comparison of four methods using the SF-36 [PDF]
We describe and compare four different methods for estimating sample size and power, when the primary outcome of the study is a Health Related Quality of Life (HRQoL) measure. These methods are: 1.
Walters, Stephen J.
core +3 more sources
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source
A cross-sectional study of QOL of diabetic patients at tertiary care hospitals in Delhi
Background: According to WHO estimates India will be the global capital of diabetes by 2025, accounting for 57.2 million diabetics. Worsening the situation is the fact that diabetes affects the economically productive age-group (45-65 years) in ...
Gautam Yogesh +4 more
doaj
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Validation and calibration of the SF-36 health transition question against an external criterion of clinical change in health status. [PDF]
PURPOSE: Cross-sectional surveys depend on retrospective health transition questions (HTQ) to estimate recent changes in health status. This paper assesses the validity of the SF-36 HTQ and calibrates its categories against change assessed prospectively ...
King, MT, Knox, SA
core +1 more source

