Results 91 to 100 of about 216,446 (286)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Comparison of SF-6D and EQ-5D Scores in Patients With Breast Cancer. [PDF]

Iran Red Crescent Med J, 2016
Utility values are a key component of a cost-utility analysis. The EQ-5D and SF-6D are two commonly used measures for deriving utilities. Of particular importance is assessing the performance of these instruments in terms of validity.This study aimed to compare the performance of the EQ-5D and the SF-6D in different states of breast cancer.This was a ...
Yousefi M, Najafi S, Ghaffari S, Mahboub-Ahari A, Ghaderi H.   +4 more
europepmc   +5 more sources

What is the evidence for the performance of generic preference-based measures? A systematic overview of reviews [PDF]

, 2017
OBJECTIVE: To assess the evidence on the validity and responsiveness of five commonly used preference-based instruments, the EQ-5D, SF-6D, HUI3, 15D and AQoL, by undertaking a review of reviews.
Brazier, J.E., Finch, A.P., Mukuria, C.
core   +1 more source

Thermo‐Mechanically Recyclable Smart Textiles from Circularly Knitted Liquid Crystal Elastomer Fibers

Advanced Functional Materials, EarlyView.
Reprogrammable multi‐material smart textiles knitted from liquid crystal elastomer fibers undergo 2D and 3D deformation under thermal and photo stimuli. Circularly knitted tubular structures reversibly contract in radial and axial directions, enabling autonomous climbing, liquid release, and micro pumping.
Xue Wan, Tongxiang Deng, Linda Plaude, Bo Gao, Siyao Chen, Fabien Sorin, Kaspar M. B. Jansen, Kun Zhou, Albert P. H. J. Schenning   +8 more
wiley   +1 more source

Relationship Between Physical Function and Health Utility in Patients Undergoing Surgical Treatment for Malignant Pleural Mesothelioma

Integrative Cancer Therapies, 2021
Purpose: Health utility, which is a measure of patient-reported outcome (PRO), has recently been used in health-related quality of life for patients with various cancers.
Takashi Tanaka BSc, Shinichiro Morishita PhD, Masaki Hashimoto PhD, MD, Toru Nakamichi MD, Yuki Uchiyama PhD, MD, Seiki Hasegawa PhD, MD, Kazuhisa Domen PhD, MD   +6 more
doaj   +1 more source

Exploring the Use of Cost-Benefit Analysis to Compare Pharmaceutical Treatments for Menorrhagia [PDF]

, 2015
Background: The extra-welfarist theoretical framework tends to focus on health-related quality of life, whilst the welfarist framework captures a wider notion of well-being.
D Husereau, DK Whynes, E McIntosh, Emma Frew, HA Glick, J Gupta, Janesh Kumar Gupta, Joe Kai, L Curtis, M Haefeli, M Shapley, MF Drummond, National Collaborating Centre for Women’s and Children’s Health, National Institute of Health and Clinical Excellence, National Institute of Health and Clinical Excellence, P Shackley, P Shackley, RD Smith, RD Smith, RW Shaw, S Birch, S Sanghera, S Sanghera, Sabina Sanghera, Tracy Elizabeth Roberts   +24 more
core   +4 more sources

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

Advanced Healthcare Materials, EarlyView.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli, Clara M.G. de Faria, Veronica Torresan, Maria Assunta Lacavalla, Mattia Cattelan, Denis Badocco, Paolo Pastore, Pasquina Marzola, Laura Cansolino, Cinzia Ferrari, Ian Postuma, Riccardo Vago, Silva Bortolussi, Antonello E. Spinelli, Daniel Forrer, Vincenzo Amendola   +15 more
wiley   +1 more source

A Bayesian Nonparametric Approach for Modeling SF-6D Health State Utility Scores

Value in Health Regional Issues, 2022
Typically, models that were used for health state valuation data have been parametric. Recently, many researchers have explored the use of nonparametric Bayesian methods in this field. In this article, we report on the results from using a nonparametric model to predict a Bayesian short-form 6-dimension (SF-6D) health state valuation algorithm along ...
openaire   +2 more sources

Impact of diagnosis of diabetes on health-related quality of life among high risk individuals: the Diabetes Prevention Program outcomes study [PDF]

, 2013
Purpose The purpose of this study is to assess if diagnosis of type 2 diabetes affected health-related quality of life (HRQoL) among participants in the Diabetes Prevention Program/Diabetes Prevention Program Outcome Study and changes with treatment ...
Ackermann, R., Barrett-Connor, E., de Groot, M., DPPOS Research Group, Florez, H., Marrero, D., Montez, M., Pan, Q., Percy, C., Rubin, R. R., Zhang, P.   +10 more
core   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source