Results 201 to 210 of about 216,446 (286)

Assessments of Health Utilities in Patients With Metabolic Dysfunction-Associated Steatohepatitis: Cross-Walk Between Disease-Specific Chronic Liver Disease Questionnaire, Short Form SF-6D, and EuroQol EQ-5D Instruments. [PDF]

Gastro Hep Adv
Younossi ZM, Stepanova M, Kim Y, Dodge S, Labriola D, Taub R, Nader F.   +6 more
europepmc   +1 more source

Examining the Feasibility and Acceptability of Valuing the Arabic Version of SF-6D in a Lebanese Population. [PDF]

Int J Environ Res Public Health, 2020
Kharroubi SA, Beyh Y, Harake MDE, Dawoud D, Rowen D, Brazier J.   +5 more
europepmc   +1 more source

Palaeolandscape reconstruction of a shallow coastal embayment in Kattegat, Denmark—influence of sea‐level changes during the latest Pleistocene and Holocene

Boreas, EarlyView.
We analyse the geological processes of a coastal embayment in the Kattegat. Using high‐resolution seismic data and sediment cores, we describe a geological evolution from glacial to shallow marine stages with a variety of preserved facies from different depositional settings, including glacio‐lacustrine, telmatic, limnic and coastal environments.
Katrine Juul Andresen, Lars Ole Boldreel, Ole Bennike, Christof Pearce, Mikkel Fruergaard, Verner Brandbyge Ernstsen, Aart Kroon, Nicole Rita Posth, Marit‐Solveig Seidenkrantz   +8 more
wiley   +1 more source

A11 Peptide Enhances Radiosensitivity by Degrading EphA2 in Nasopharyngeal Carcinoma

Cancer Science, EarlyView.
In EphA2‐high‐expressing nasopharyngeal carcinoma cells, radiation triggers RSK‐dependent phosphorylation of EphA2 at Ser897, which in turn activates AKT and promote radioresistance. The A11 peptide breaks this signaling cascade by degrading EphA2 and blocking its S897 phosphorylation, thereby markedly enhancing radiosensitivity.
Ming Zhang, Zhi‐Qiang Xiao, Wei Huang, Shan‐Shan Lu, Hong Yi, Juan Feng   +5 more
wiley   +1 more source

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

Cancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang, Hongshi Cai, Yue Zhu, Jianfeng Liang, Hongyu Li, Fan Song, Ziyi Wang, Jinsong Hou   +7 more
wiley   +1 more source

Beauveria Bassiana Triggers Soybean Systemic Resistance and Causes Sublethal Effects in Spodoptera frugiperda

Entomologia Experimentalis et Applicata, EarlyView.
The interaction of soybean plant and the endophytic microorganism Beauveria bassiana was evaluated by inoculating a single trifoliate leaf. The effects of this inoculation on the herbivory, larval development, and life traits of Spodoptera frugiperda were measured.
Carla Mariane Marassatto, Lucia Pires Ferreira, Joel da Cruz Couceiro, Marta Rodrigues de Oliveira, Aline Sartori Guidolin, Italo Delalibera Jr.   +5 more
wiley   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

The FEBS Journal, EarlyView.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima, Dev Sriranganadane, Daiane Laise da Silva, Natália C. Drebes Dörr, Enzo Breviglieri Sichi Mello, Caio Vinicius dos Reis, Rogério Ferreira Lourenço, José Felipe Teixeira da Silva Santos, Anita Salmazo, Brenno Wendler Miranda, Katlin B. Massirer, Rafael M. Couñago, Cristina E. Alvarez‐Martinez   +12 more
wiley   +1 more source

Welfare and Physiological Consequences of Non‐Lethal Blood Sampling From the Caudal Vasculature of Atlantic Salmon (Salmo salar L.)

Journal of Fish Diseases, EarlyView.
ABSTRACT The objective of this study was to evaluate welfare and health effects following single and repeated non‐lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6‐week freshwater experiment with fish weighing 50–100 g, undergoing up to four blood withdrawals, and a
Harriet Romstad, Camilla Karlsen, Silje Stensby‐Skjærvik, Alf Seljenes Dalum, Maria Banaszkiewicz, Simen Foyn Nørstebø, Jessica Louise Ray, Hege Lund, Torstein Kristensen, Christine Klykken   +9 more
wiley   +1 more source

The dental plate on bichir pectoral fins: A unique dermal skeletal element bearing individual odontodes with tooth‐like replacement

Journal of Anatomy, EarlyView.
Pectoral fins of bichirs encompass the so‐called dental plates – unique dermal skeletal elements with individual odontodes identical to the oral teeth. Abstract The dermal skeleton appeared early in vertebrate evolution in the form of mineralized skin denticles composed of tooth‐like units—odontodes.
Tomáš Suchánek, Ann Huysseune, Robert Cerny   +2 more
wiley   +1 more source