Results 71 to 80 of about 216,446 (286)

EQ-5D in skin conditions: an assessment of validity and responsiveness [PDF]

, 2014
Aims and objectives This systematic literature review aims to assess the reliability, validity and responsiveness of three widely used generic preference-based measures of health-related quality of life (HRQL), i.e., EQ-5D, Health Utility Index 3 (HUI3 ...
AFN Klassen, BF O’donnell, C Moberg, D Feeny, D Papaioannou, D Revicki, DF Cella, E Christophers, E Daudén, GH Guyatt, GR Barton, J Brazier, J Brazier, J Brazier, J Dowie, J Tosh, JE Brazier, John Brazier, K Reich, L Longworth, L Longworth, L Matusiak, Louise Longworth, M Herdman, NICE, NICE, NJ Bansback, P Dolan, P Swinburn, PCM Kerkhof Van De, R Brooks, R Shikiar, R Shikiar, RJ Lasek, S Weiss, SCR Weiss, SJ Walters, T Luger, V Brodszky, Yaling Yang   +39 more
core   +3 more sources

Estimating population cardinal health state valuation models from individual ordinal (rank) health state preference data [PDF]

, 2010
Ranking exercises have routinely been used as warm-up exercises within health state valuation surveys. Very little use has been made of the information obtained in this process.
McCabe, C., Brazier, J., Gilks, P., Tsuchiya, A., Roberts, J., O'Hagan, A., Stevens, K.   +6 more
core   +2 more sources

Comparison of EQ-5D and SF-6D utilities in mental health patients [PDF]

Health Economics, 2006
Various preference-based measures of health are available for use as an outcome measure in cost-utility analysis. The aim of this study is to compare two such measures EQ-5D and SF-6D in mental health patients. Baseline data from a Dutch multi-centre randomised trial of 616 patients with mood and/or anxiety disorders were used.
Lamers, L.M., Bouwmans, C.A., van Straten, A., Donker, M.C., Hakkaart, L.   +4 more
openaire   +2 more sources

Complications among colorectal cancer survivors: SF-6D preference-weighted quality of life scores [PDF]

, 2011
Background Societal preference-weighted health-related quality of life (HRQOL) scores enable comparing multi-dimensional health states across diseases and treatments for research and policy. Objective To assess the effects of living with a permanent
Alschuler, Andrea, Baldwin, Carol M., Coons, Stephen Joel, Grant, Marcia, Green, Sylvan B., Herrinton, Lisa J., Hornbrook, Mark C., Krouse, Robert S., McMullen, Carmit K., Mohler, M. Jane, Rawl, Susan M., Wendel, Christopher S.   +11 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Disability, physical activity, and health-related quality of life in Australian adults: An investigation using 19 waves of a longitudinal cohort

PLoS ONE, 2022
Background Any form of long-term physical or mental impairment might negatively influence health-related quality of life (HRQoL). HRQoL, as an independent concept, covers a wide range of characteristics that includes physical, mental, social, and ...
Syed Afroz Keramat, Benojir Ahammed, Aliu Mohammed, Abdul-Aziz Seidu, Fariha Farjana, Rubayyat Hashmi, Kabir Ahmad, Rezwanul Haque, Sazia Ahmed, Mohammad Afshar Ali, Bright Opoku Ahinkorah   +10 more
doaj   +2 more sources

The impact of diabetes mellitus and other chronic medical conditions on health-related Quality of Life: Is the whole greater than the sum of its parts?

Health and Quality of Life Outcomes, 2005
Background Diabetes mellitus (DM) is an important public health concern, the impact of which is increased by the high prevalence of co-existing chronic medical conditions among subjects with DM.
Fong Kok-Yong, Li Shu-Chuen, Cheung Yin-Bun, Wee Hwee-Lin, Thumboo Julian   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mapping the PHQ-8 to EQ-5D, HUI3 and SF6D in patients with depression

BMC Psychiatry, 2021
Background There is limited evidence of mapping clinical instruments to a generic preference-based instrument in Asian patient populations. The current study aims to map the eight-item Patient Health Questionnaire depression scale (PHQ-8) onto the ...
Edimansyah Abdin, Siow Ann Chong, Esmond Seow, Kelvin Bryan Tan, Mythily Subramaniam   +4 more
doaj   +1 more source

Cost-effectiveness of Spa treatment for fibromyalgia: general health improvement is not for free [PDF]

, 2007
Objectives: To estimate the cost-effectiveness of an adjuvant treatment course of spa treatment compared with usual care only in patients with fibromyalgia syndrome (FM).
Braakman-Jansen, L.M.A., Laar, M.A.F.J. van de, Rasker, J.J., Taal, E., Zijlstra, T.R.   +4 more
core   +3 more sources