Abstract Aim To assess health utility values in the Semaglutide Treatment Effect in People with obesity (STEP) 1‐4 trials. Materials and Methods The STEP 1‐4 phase 3a, 68‐week, double‐blind randomized controlled trials assessed the efficacy and safety of semaglutide 2.4 mg versus placebo in individuals with a body mass index (BMI) of 30 kg/m2 or higher
Jakob Bue Bjorner +3 more
wiley +1 more source
Abstract Introduction This study aimed to assess patients' preferences of nonsurgical treatments for chronic low back pain (CLBP). Method We conducted a discrete choice experiment (DCE) in Quebec, Canada, in 2018. Seven attributes were included: treatment modality, pain reduction, the onset of treatment efficacy, duration effectiveness, difficulties ...
Gabin F. Morillon +3 more
wiley +1 more source
Valuing the SF-6Dv2 Classification System in the United Kingdom Using a Discrete-choice Experiment With Duration [PDF]
Objective: An updated version of the SF-6D Classification System (SF-6Dv2) has been developed, and utility value sets are required. The aim of this study was to test the development of a United Kingdom SF-6Dv2 value set, and address limitations of the existing SF-6D value set (which results in a narrow range of utilities). This
Mulhern, B.J. +3 more
openaire +3 more sources
Background Chronic rhinosinusitis with or without nasal polyps (CRSwNP/CRSsNP) seriously impairs health‐related quality of life (HRQoL). This analysis describes the impact of the exhalation delivery system with fluticasone (EDS‐FLU) on HRQoL, assessed by the 36‐item Short‐Form Health Survey version 2 (SF‐36v2), and on utilities, assessed via the Short ...
Zachary M. Soler +3 more
wiley +1 more source
Estimating a Preference-Based Value Set for the Mental Health Quality of Life Questionnaire (MHQoL) [PDF]
Background: Health economic evaluations using common health-related quality of life measures may fall short in adequately measuring and valuing the benefits of mental health care interventions. The Mental Health Quality of Life questionnaire (MHQoL) is a
Brouwer, Werner B.F. +4 more
core +1 more source
Consistency between three different ways of administering the Short Form 6 Dimension version 2 [PDF]
Background The Short Form 6 Dimension (SF-6D) is a multi-attribute utility instrument derived from the Short-Form 36 Health Survey Version 2 (SF-36v2) quality of life questionnaire and is used to calculate quality-adjusted life years (QALYs) on a ...
Brazier, J.E. +3 more
core +1 more source
Obtaining SF-6D utilities from FACT-H&N in thyroid carcinoma patients: development and results from a mapping study [PDF]
ObjectiveThere is limited evidence for mapping clinical tools to preference-based generic tools in the Chinese thyroid cancer patient population. The current study aims to map the FACT-H&N (Functional Assessment of Cancer Therapy-Head and Neck Cancer)
Deyu Huang +4 more
core +1 more source
An artificial therapist (manage your life online) to support the mental health of youth: Co-design and case series [PDF]
Background: The prevalence of child and adolescent mental health issues is increasing faster than the number of services available, leading to a shortfall. Mental health chatbots are a highly scalable method to address this gap.
Anderson, Georgia +11 more
core +2 more sources
Criteria for developing, assessing and selecting candidate EQ-5D bolt-ons. [PDF]
PURPOSE: 'Bolt-on' dimensions are additional items added to multi-attribute utility instruments (MAUIs) such as EQ-5D that measure constructs not included in the core descriptive system.
Addo, R +8 more
core +1 more source
Estimating a preference-based single index measuring the quality of life impact of self-management for diabetes [PDF]
Objective. Self-management is becoming increasingly important in diabetes but is neglected in conventional preference-based measures. The objective of this paper was to generate health state utility values for a novel classification system measuring the ...
Alexander Labeit +13 more
core +2 more sources

