Results 31 to 40 of about 307,545 (230)

GROSS MOTOR FUNCTION CLASSIFICATION SYSTEM AND MANUAL ABILITY CLASSIFICATION IN CEREBRAL PALSY EVALUATION [PDF]

open access: yesRomanian Journal of Pediatrics, 2016
Cerebral palsy (CP) is a chronically cerebral disease, which is defined like a group of non-progressives motor diseases that onset in the first year of life and are the secondary lesions for a developed brain.
Ioana Grigore   +4 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Screen-Printed Superconducting Y-Ba-Cu-O Thick Films on Various Substrates

open access: yesActive and Passive Electronic Components, 1989
Superconducting thick films of the Y-Ba-Cu-O system prepared by screen-printing and sintering on different substrates were investigated to study the effect of the substrate material on the superconducting properties of the films.
T. Kokkomäki   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Clinical implications and current perspectives of statin-induced rhabdomyolysis syndrome – case presentation

open access: yesRomanian Journal of Cardiology, 2022
Though rare, statins can produce serious adverse effects with clinical implications that urge prompt intervention. However, in high-risk patients that require intense hypolipemiant treatment, such situations can be challenging and require complimentary ...
Ciobanu Elena Cosmina   +4 more
doaj   +1 more source

CD8-Lymphocytic Phenotype Significance in Primary Multiple and Familial Melanoma with Various CDKN2A Mutational Status

open access: yesMedicina, 2023
Background and Objectives: In the realm of the rising incidence of cutaneous and mucous melanoma, CDKN2A mutations characterize familial and multiple primary melanoma cases.
Luana-Andreea Boşoteanu   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Algorithm of search and track of static and moving large-scale objects

open access: yesITM Web of Conferences, 2017
We suggest an algorithm for processing of a sequence, which contains images of search and track of static and moving large-scale objects. The possible software implementation of the algorithm, based on multithread CUDA processing, is suggested ...
Kalyaev Anatoly, Khisamutdinov Maxim
doaj   +1 more source

BISPHOSPHONATE THERAPY IN PEDIATRIC PATIENTS WITH OSTEOGENESIS IMPERFECTA [PDF]

open access: yesRomanian Journal of Pediatrics, 2015
Osteogenesis imperfecta (OI) is a group of rare inherited disorders of connective tissue with the common feature of excessive fragility of bones caused by mutations in collagen. We present the case of 2 patients diagnosed with different types of OI, both
Alina Murgu   +4 more
doaj   +1 more source

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