Results 41 to 50 of about 25,430 (297)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Research on Multi-View 3D Reconstruction Technology Based on SFM

Sensors, 2022
Multi-view 3D reconstruction technology is used to restore a 3D model of practical value or required objects from a group of images. This paper designs and implements a set of multi-view 3D reconstruction technology, adopts the fusion method of SIFT and ...
Lei Gao, Yingbao Zhao, Jingchang Han, Huixian Liu   +3 more
doaj   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

MOBILIZATION OF SPLENIC FLEXURE DURING RECTAL RESECTION

Сибирский онкологический журнал, 2017
Background. Splenic flexure mobilization (SFM) is a difficult step within both conventional and laparoscopic procedures, often associated with intra- and postoperative morbidity.
I. L. Chernikovsky, I. I. Aliev, А. А. Smirnov, N. V. Savanovich, А. V. Gavrilyukov   +4 more
doaj   +1 more source

The “refugee crisis” as an opportunity structure for right-wing populist social movements: The case of PEGIDA

Studies in Communication Sciences, 2021
Current research on right-wing populist communication is often confined to political parties, with social movements receiving much less attention. To help fill this research gap, we examine the frames and master frames of the PEGIDA movement and the role
Marco Bitschnau, Dennis Lichtenstein, Birte Fähnrich   +2 more
doaj   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

Prix Master 2016 de la SFM [PDF]

médecine/sciences, 2017
In the normal course of muscle fiber development, myonuclei actively position and adapt a precise localization in mature fibers, shaping MyoNuclear Domains (MNDs). Myonuclei positioning in fibers appears to be essential for muscle function as defects in MNDs settings are always associated with dysfunction (i.e., centronuclear myopathy, sarcopenia ...
Nathalie Couturier, Vincent Gache
openaire   +1 more source

Tough and Temperature‐Resistant Material Based on Bombyx mori Silk Fibroin

Advanced Science, EarlyView.
We propose a biomimetic “Hydration‐Crystallization Locking” (HCL) strategy inspired by Bombyx mori spinning to enhance silk fibroin (SF) performance in extreme temperatures. A flexible fibroin membrane (FFM) shows high strength, toughness, and shape retention under −196°C and 70°C.
Meng Zhang, Quan Wan, Yajun Shuai, Qi Wu, Jing Yu, Mingzheng Fang, Yuqing Zhang, Chuanbin Mao, Mingying Yang   +8 more
wiley   +1 more source

Transformation of operational management of machine tools, machine complexes operation with the help of «Operational Management System»

Омский научный вестник
The article focuses on the potential integration of the SFM digital control system into production. To achieve a more accurate implementation of the dSFM system, the article identifies its strengths and weaknesses.
О. P. Korzhova, D. S. Makashin, P. E. Popov, I. E. Donoaga, А. V. Obryvalin   +4 more
doaj   +1 more source

Extreme Kinetic Stability and RNase Resistance of Human Telomerase RNA G‐Quadruplexes Overcome by DHX36 Helicase

Advanced Science, EarlyView.
The RNA G‐quadruplexes formed at the 5'‐end of the RNA component of human telomerase possess extreme slow unfolding rate, rendering them resistant to nuclease degradation. The helicase DHX36 overcame this kinetic barrier and significantly reduced the folded fraction.
Qun Luo, Yashuo Zhang, Yingxian Qian, Huiying Zhan, Wenqiang Wu, Huijuan You   +5 more
wiley   +1 more source